Solute Carrier Family 35 (UDP-GlcNAc/UDP-Glucose Transporter), Member D2 (SLC35D2) (C-Term) antibody
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- Target See all Solute Carrier Family 35 (UDP-GlcNAc/UDP-Glucose Transporter), Member D2 (SLC35D2) Antibodies
- Solute Carrier Family 35 (UDP-GlcNAc/UDP-Glucose Transporter), Member D2 (SLC35D2)
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunofluorescence (IF)
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- 14 amino acid synthetic peptide near the carboxy terminus of Human SLC35D2
- Isotype
- IgG
- Top Product
- Discover our top product SLC35D2 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS, 0.02 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Solute Carrier Family 35 (UDP-GlcNAc/UDP-Glucose Transporter), Member D2 (SLC35D2)
- Alternative Name
- SLC35D2 / UGTREL8 (SLC35D2 Products)
- Synonyms
- 5730408I21Rik antibody, SQV7L antibody, UGTrel8 antibody, hfrc antibody, mUGTrel8 antibody, solute carrier family 35, member D2 antibody, Slc35d2 antibody
- Background
- The solute carrier family SLC35 consists of at least 17 proteins that act as nucleotide sugar transporters localized to the Golgi apparatus and endoplasmic reticulum. The role of the ER-resident SLC family member SLC35D2 is to transport both UDP-glucuronic acid and UDP-N-acetylgalactosamine. Its overexpression in transfected cells modulated cell surface heparin sulfate expression, suggesting that SLC35D2 is involved in heparin sulfate synthesis. SLC35D2-overexpressing cells also showed increased constitutive and hypotonic stress-stimulated release of UDP-GlcNAc, suggesting that SLC35D2 may be involved in UDP-sugar release and cell signaling.Synonyms: HFRC, HFRC1, Homolog of Fringe connection protein 1, SQV7-like protein, SQV7L, Solute carrier family 35 member D2, UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter, UDP-galactose transporter-related protein 8
- Gene ID
- 11046
- NCBI Accession
- NP_008932
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