AES antibody (AA 79-91)

Catalog No. ABIN1494461

Product Details anti-AES Antibody

Target: AES (Amino-terminal Enhancer of Split (AES))

Binding Specificity: AA 79-91

Reactivity: Human, Mouse, Rat, Cow, Dog, Xenopus laevis, Hamster

Host: Goat

Clonality: Polyclonal

Conjugate: This AES antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human AES / GRG / Groucho. This antibody is expected to recognize all reported isoforms (NP_945320.1, NP_001121.2, NP_945321.1).

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Mouse, Rat, Hamster, Elephant, Dog, Bovine, Opossum, Xenopus, Frog (100%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide SHLPQQLKFTTSD-C from the N-terminus of human AES / GRG / Groucho (NP_945320.1, NP_001121.2, NP_945321.1). Percent identity by BLAST analysis: Human, Gorilla, Mouse, Rat, Hamster, Elephant, Dog, Bovine, Opossum, Xenopus, Frog (100%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:64000), WB (0.3 - 1 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Approx 30kD band observed in Human Brain (Cerebellum and Cerebral Cortex) lysates (calculated MW of 29.1kD according to NP_945320.1). Recommended concentration: 0.3-1 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for AES

Target: AES (Amino-terminal Enhancer of Split (AES))

Alternative Name: AES / Groucho (AES Products)

Synonyms: AES-1 antibody, AES-2 antibody, ESP1 antibody, GRG antibody, GRG5 antibody, TLE5 antibody, AL024115 antibody, Esp1 antibody, Grg antibody, Grg-5 antibody, Grg5 antibody, Tle5 antibody, zgc:64216 antibody, aes-1 antibody, aes-2 antibody, esp1 antibody, grg antibody, grg5 antibody, tle5 antibody, xgrg-5 antibody, AES antibody, amino-terminal enhancer of split antibody, amino-terminal enhancer of split S homeolog antibody, AES antibody, Aes antibody, aes antibody, aes.S antibody

Background: Name/Gene ID: AES
Family: Transcription factor

Synonyms: AES, AES-1, AES-2, Amino enhancer of split, ESP1, Groucho, GRG, Protein ESP1, TLE5, Protein GRG, gp130-associated protein GAM, GRG5

Gene ID: 166

NCBI Accession: NP_945320, NP_001121, NP_945321

UniProt: Q08117

Pathways: WNT Signaling, SARS-CoV-2 Protein Interactome