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Dynamitin antibody (AA 50-320)

DCTN2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1512818
  • Target See all Dynamitin (DCTN2) Antibodies
    Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
    Binding Specificity
    • 15
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-320
    Reactivity
    • 40
    • 35
    • 17
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 48
    • 5
    • 3
    Rabbit
    Clonality
    • 53
    • 3
    Polyclonal
    Conjugate
    • 31
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Dynamitin antibody is un-conjugated
    Application
    • 44
    • 17
    • 13
    • 13
    • 9
    • 8
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequence
    HIIVNPNAAY DKFKDKRVGT KGLDFSDRIG KTKRTGYESG EYEMLGEGLG VKETPQQKYQ RLLHEVQELT TEVEKIKTTV KESATEEKLT PVLLAKQLAA LKQQLVASHL EKLLGPDAAI NLTDPDGALA KRLLLQLEAT KNSKGGSGGK TTGTPPDSSL VTYELHSRPE QDKFSQAAKV AELEKRLTEL ETAVRCDQDA QNPLSAGLQG ACLMETVELL QAKVSALDLA VLDQVEARLQ SVLGKVNEIA KHKASVEDAD TQSKVHQLYE T
    Cross-Reactivity
    Human, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 50-320 of human DCTN2 (NP_006391.1).
    Isotype
    IgG
    Top Product
    Discover our top product DCTN2 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IF,1:20 - 1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
    Alternative Name
    DCTN2 (DCTN2 Products)
    Synonyms
    DCTN2 antibody, dctn2 antibody, dctn50 antibody, dynamitin antibody, rbp50 antibody, CG8269 antibody, DMN antibody, Dmel\\CG8269 antibody, P50 antibody, dDyn antibody, dmn antibody, dyna antibody, l(2)k16109 antibody, l(2)k16218 antibody, p50 antibody, p50/Dmn antibody, p50/dynamitin antibody, 2310042E05Rik antibody, C130077D06Rik antibody, C87049 antibody, DCTN-50 antibody, GMP23-48K antibody, RBP50 antibody, DCTN50 antibody, DYNAMITIN antibody, zgc:63867 antibody, dynactin subunit 2 antibody, dynactin subunit 2 S homeolog antibody, Dynactin 2, p50 subunit antibody, dynactin 2 antibody, dynactin 2 (p50) antibody, dynactin subunit 2 L homeolog antibody, DCTN2 antibody, dctn2.S antibody, DCTN2-p50 antibody, dctn2 antibody, Dctn2 antibody, dctn2.L antibody
    Background
    This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,DCTN2,DCTN50,DYNAMITIN,HEL-S-77,RBP50,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cytoskeleton,Motor Proteins,Neuroscience,Neurodegenerative Diseases,DCTN2
    Molecular Weight
    44 kDa
    Gene ID
    10540
    UniProt
    Q13561
    Pathways
    M Phase, Ribonucleoprotein Complex Subunit Organization
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