ATM antibody (Ataxia Telangiectasia Mutated) (full length)

Details for Product anti-ATM Antibody No. ABIN151775, Supplier: Log in to see
Antigen
  • ATM
  • Atm
  • CG6535
  • Dmel\\CG6535
  • Tefu
  • atm
  • atm/tefu
  • dATM
  • tef
  • Xatm
  • at1
  • atdc
  • tel1
  • telo1
  • AT1
  • ATA
  • ATC
  • ATD
  • ATDC
  • ATE
  • TEL1
  • TELO1
  • AI256621
  • C030026E19Rik
  • telomere fusion
  • ATM serine/threonine kinase L homeolog
  • ATM serine/threonine kinase
  • ataxia telangiectasia mutated
  • ataxia telangiectasia mutated (atm)
  • serine/threonine-protein kinase ATM
  • tefu
  • atm.L
  • atm
  • ATM
  • EDI_100660
  • CpipJ_CPIJ001772
  • BDBG_08252
  • PAAG_02532
  • MCYG_05088
  • VDBG_06833
  • ACLA_015700
  • LOC5565620
  • MGYG_07634
  • PGTG_14279
  • Atm
Alternatives
anti-Hamster ATM antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
full length
89
36
18
17
16
16
10
6
6
6
6
6
6
5
5
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Monkey, Mouse (Murine), Rat (Rattus)
368
160
82
27
8
1
1
Host
Mouse
248
102
11
8
3
1
Clonality (Clone)
Monoclonal ()
Conjugate
This ATM antibody is un-conjugated
11
11
9
8
7
6
5
5
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Chromatin Immunoprecipitation (ChIP), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
233
136
121
95
81
56
52
44
27
22
13
8
4
4
2
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Immunogen Recombinant protein expressed in E. coli corresponding to amino acids 2577-3056.
Clone 2C1
Isotype IgG1
Specificity This antibody recognizes full-length ATM, a 350- kDa nuclear phosphoprotein.
Purification Protein G purified
Plasmids, Primers & others Plasmids, Primers & others ATM products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name ATM (ATM Antibody Abstract)
Background Gene Symbol: ATM
Molecular Weight Theoretical MW: 370 kDa
Gene ID 472
UniProt Q13315
Pathways p53 Signaling, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
Application Notes Western Blot 1:500-1:3000, Chromatin Immunoprecipitation 1:10 - 1:500, Flow Cytometry, ELISA 1:100 - 1:2000, Immunohistochemistry 10 - 1:500, Immunocytochemistry/Immunofluorescence, Immunoprecipitation 1-10 μg/mL, Immunohistochemistry-Paraffin 5 μg/mLIHC-R. ICC/IF usage reported in scientifc literature (Harry Scherthan, et.al., 2000 and Yiyoung Liu, et.al., 2006). ELISA usage reported in scientific literature. WB: Predicted molecular weight: 350 kDa. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 1.85 mg/mL
Buffer PBS ( pH 7.4)
Buffer contains: No Preservative
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage -80 °C,-20 °C
Storage Comment Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Detection of ATM (Anti-ATM 2C1, ABIN151775) or ATR by western blot in human Raji whol...
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Western Blot: ATM Antibody (2C1) [ABIN151775] - A. 30 ug U87-MG whole cell lysate/ext...
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Western Blot: ATM Antibody (2C1) [ABIN151775] - A. 30 ug NT2D1 whole cell lysate/extr...
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Western Blot: ATM Antibody (2C1) [ABIN151775] - analysis of ATM in U2OS sarcoma cells...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Immunohistochemistry-Paraffin: ATM Antibody (2C1) [ABIN151775] - Human Testis (formal...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Immunohistochemistry-Paraffin: ATM Antibody (2C1) [ABIN151775] - Human Kidney (formal...
Product cited in: Simões, Martins, Ferreira: "Early intranuclear replication of African swine fever virus genome modifies the landscape of the host cell nucleus." in: Virus research, Vol. 210, pp. 1-7, 2015 (PubMed).

Park, Kong, Kim, Lee, Park: "Inhibition of S-adenosylhomocysteine hydrolase decreases cell mobility and cell proliferation through cell cycle arrest." in: American journal of cancer research, Vol. 5, Issue 7, pp. 2127-38, 2015 (PubMed). Further details: Western Blotting

Batenburg, Thompson, Hendrickson, Zhu: "Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation." in: The EMBO journal, Vol. 34, Issue 10, pp. 1399-416, 2015 (PubMed). (Sample species: Mouse (Murine)). Further details: Western Blotting

Vermezovic, Adamowicz, Santarpia, Rustighi, Forcato, Lucano, Massimiliano, Costanzo, Bicciato, Del Sal, dAdda di Fagagna: "Notch is a direct negative regulator of the DNA-damage response." in: Nature structural & molecular biology, Vol. 22, Issue 5, pp. 417-24, 2015 (PubMed). (Sample species: Human). Further details: Western Blotting,Immunohistochemistry (Paraffin-embedded Sections)

Muraki, Han, Miller, Murnane: "Processing by MRE11 is involved in the sensitivity of subtelomeric regions to DNA double-strand breaks." in: Nucleic acids research, Vol. 43, Issue 16, pp. 7911-30, 2015 (PubMed). (Sample species: Human). Further details: Western Blotting

Gutiérrez-González, Belda-Iniesta, Bargiela-Iparraguirre, Dominguez, García Alfonso, Perona, Sanchez-Perez: "Targeting Chk2 improves gastric cancer chemotherapy by impairing DNA damage repair." in: Apoptosis : an international journal on programmed cell death, Vol. 18, Issue 3, pp. 347-60, 2013 (PubMed). (Sample species: Human). Further details: Western Blotting

Min, Bruhn, Grigaravicius, Zhou, Li, Krüger, Siddeek, Greulich, Popp, Meisezahl, Calkhoven, Bürkle, Xu, Wang: "Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation." in: Nature communications, Vol. 4, pp. 2993, 2013 (PubMed). (Sample species: Mouse (Murine)). Further details: Western Blotting

Murad, Cullen, McKenzie, Ryan, Thorburn, Gueven, Kobayashi, Birrell, Yang, Dörk, Becherel, Grattan-Smith, Lavin: "Mitochondrial dysfunction in a novel form of autosomal recessive ataxia." in: Mitochondrion, Vol. 13, Issue 3, pp. 235-45, 2013 (PubMed). (Sample species: Human). Further details: Western Blotting

Simões, Martins, Ferreira: "Host DNA damage response facilitates African swine fever virus infection." in: Veterinary microbiology, Vol. 165, Issue 1-2, pp. 140-7, 2013 (PubMed).

Hao, Duncan, Su, Li, Silvester, Hong, You, Brenner, Gorrini, Haight, Wakeham, You-Ten, McCracken, Elia, Li, Detmar, Jurisicova, Hobeika, Reth, Sheng, Lang, Ohashi, Zhong, Wang, Mak: "The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis." in: The Journal of experimental medicine, Vol. 209, Issue 1, pp. 173-86, 2012 (PubMed).

Kang, So, Ouchi: "Deregulation of DNA damage response pathway by intercellular contact." in: The Journal of biological chemistry, Vol. 287, Issue 20, pp. 16246-55, 2012 (PubMed). Further details: Western Blotting

Zhang, de Toledo, Pandey, Guo, Pain, Li, Azzam: "Role of the translationally controlled tumor protein in DNA damage sensing and repair." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 16, pp. E926-33, 2012 (PubMed).

Ai, Skehan, Saydi, Lin, Brown: "Ataxia-Telangiectasia, Mutated (ATM)/Nuclear Factor κ light chain enhancer of activated B cells (NFκB) signaling controls basal and DNA damage-induced transglutaminase 2 expression." in: The Journal of biological chemistry, Vol. 287, Issue 22, pp. 18330-41, 2012 (PubMed). (Sample species: Human). Further details: ELISA

Yan, Greer, Cao, Kolb, Cowan: "RAC1 GTPase plays an important role in γ-irradiation induced G2/M checkpoint activation." in: Breast cancer research : BCR, Vol. 14, Issue 2, pp. R60, 2012 (PubMed). (Sample species: Human). Further details: Western Blotting

Hsu, Lee, Yeh, Chen, Wu, Wang, Chen, Hung, Liu, Chen, Hsiao, Wang, Tsou, Tsou, Wu, Chang, Lin: "58-kDa microspherule protein (MSP58) is novel Brahma-related gene 1 (BRG1)-associated protein that modulates p53/p21 senescence pathway." in: The Journal of biological chemistry, Vol. 287, Issue 27, pp. 22533-48, 2012 (PubMed). (Sample species: Human). Further details: Western Blotting

Mahajan, Coppola, Rawal, Chen, Lawrence, Engelman, Lawrence, Mahajan: "Ack1-mediated androgen receptor phosphorylation modulates radiation resistance in castration-resistant prostate cancer." in: The Journal of biological chemistry, Vol. 287, Issue 26, pp. 22112-22, 2012 (PubMed). (Sample species: Human). Further details: Western Blotting

Hardee, Marciscano, Medina-Ramirez, Zagzag, Narayana, Lonning, Barcellos-Hoff: "Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-β." in: Cancer research, Vol. 72, Issue 16, pp. 4119-29, 2012 (PubMed). (Sample species: Human). Further details: Western Blotting

Baritaud, Cabon, Delavallée, Galán-Malo, Gilles, Brunelle-Navas, Susin: "AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation." in: Cell death & disease, Vol. 3, pp. e390, 2012 (PubMed). Further details: Western Blotting

Shi, Felley-Bosco, Marti, Stahel: "Differential effects of lovastatin on cisplatin responses in normal human mesothelial cells versus cancer cells: implication for therapy." in: PLoS ONE, Vol. 7, Issue 9, pp. e45354, 2012 (PubMed). (Sample species: Human). Further details: Western Blotting

Sakasai, Sakai, Iimori, Kiyonari, Matsuoka, Kakeji, Kitao, Maehara: "CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 17, Issue 12, pp. 962-70, 2012 (PubMed). (Sample species: Human). Further details: Western Blotting

Did you look for something else?