Metabotropic Glutamate Receptor 5 antibody (Glutamate Receptor, Metabotropic 5) (C-Term)

Details for Product anti-GRM5 Antibody No. ABIN152473
Antigen
  • GPRC1E
  • MGLUR5
  • mGlu5
  • mGluR5
  • mGlur5
  • 6430542K11Rik
  • AI850523
  • Glu5R
  • Gprc1e
  • mGluR5b
  • glutamate receptor, metabotropic 5
  • glutamate metabotropic receptor 5
  • GRM5
  • Grm5
Alternatives
anti-Human Metabotropic Glutamate Receptor 5 antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
C-Term
82
71
15
14
11
7
4
3
3
2
2
2
2
1
Reactivity
Mouse (Murine), Rat (Rattus)
200
156
146
7
7
5
5
3
3
3
2
2
1
Host
Rabbit
110
91
4
2
Clonality
Polyclonal
Conjugate
This Metabotropic Glutamate Receptor 5 antibody is un-conjugated
9
7
7
6
6
6
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (IHC), Western Blotting (WB)
166
113
83
69
58
37
36
22
13
4
4
3
2
1
Options
Immunogen Peptide from the C-terminal region of rat mGluR5 and rat mGluR1a.
Specificity Specific for the ~125k monomer and the ~250k dimers of mGluR5 and mGluR1. Immunolabeling is blocked by preadsorption of antibody with the peptide used as antigen to generate the antibody.
Purification Immunogen affinity purified
Plasmids, Primers & others Plasmids, Primers & others Metabotropic Glutamate Receptor 5 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name MGluR5 / GRM5 (GRM5 Antibody Abstract)
Background Gene Symbol: GRM5
Gene ID 2915
UniProt P31424
Pathways Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
Application Notes Western Blot 1:1000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Frozen 1:500
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Buffer 10 mM HEPES ( pH 7.5), 0.15M NaCl, 0.1 mg/mL BSA and 50 % Glycerol
Buffer contains: 0.1 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Glutamate Receptor, Metabotropic 5 (GRM5) (C-Term) antibody (ABIN152473) Western blot of 10 ug of HEK 293 cells expressing mGluR1a and mGluR5 showing the spec...
Western Blotting (WB) image for anti-Glutamate Receptor, Metabotropic 5 (GRM5) (C-Term) antibody (ABIN152473) Western Blot: metabotropic Glutamate Receptor 5/1 Antibody [ABIN152473] - 10 ug of HE...
Product cited in: Lee, Vyas, Garner, Montgomery: "Autism-associated Shank3 mutations alter mGluR expression and mGluR-dependent but not NMDA receptor-dependent long-term depression." in: Synapse (New York, N.Y.), Vol. 73, Issue 8, pp. e22097, 2019 (PubMed). Method employed by authors: Immunofluorescence (fixed cells) (IF/ICC) (Sample species: Rat (Rattus)).

Cheyne, Grant, Butler-Munro, Foote, Connor, Montgomery: "Synaptic integration of newly generated neurons in rat dissociated hippocampal cultures." in: Molecular and cellular neurosciences, Vol. 47, Issue 3, pp. 203-14, 2011 (PubMed). (Sample species: Rat (Rattus)).

Spanagel, Pendyala, Abarca, Zghoul, Sanchis-Segura, Magnone, Lascorz, Depner, Holzberg, Soyka, Schreiber, Matsuda, Lathrop, Schumann, Albrecht: "The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption." in: Nature medicine, Vol. 11, Issue 1, pp. 35-42, 2005 (PubMed). (Sample species: Mouse (Murine)). Further details: Western Blotting

Did you look for something else?