CAMK2A antibody (Calcium/calmodulin-Dependent Protein Kinase II alpha) (pThr286)

Details for Product anti-CAMK2A Antibody No. ABIN152527
Antigen
  • camk2
  • camk2b
  • zgc:112538
  • zgc:123320
  • CAMKA
  • CaMKII
  • R74975
  • mKIAA0968
  • PK2CDD
  • PKCCD
  • calcium/calmodulin dependent protein kinase II alpha
  • calcium/calmodulin dependent protein kinase (CaM kinase) II alpha S homeolog
  • calcium/calmodulin-dependent protein kinase II alpha
  • CAMK2A
  • camk2a.S
  • camk2a
  • Camk2a
Alternatives
anti-Human CAMK2A antibody for Western Blotting
Epitope
pThr286
24
22
12
10
9
7
7
6
5
3
3
3
2
2
1
1
1
1
1
1
Reactivity
Mouse (Murine), Rat (Rattus)
150
93
88
25
6
6
4
4
3
2
2
1
1
1
1
1
1
1
1
Host
Rabbit
121
53
20
Clonality
Polyclonal
Conjugate
This CAMK2A antibody is un-conjugated
9
7
7
6
6
6
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
178
94
69
50
43
34
26
8
7
5
3
2
2
1
1
Options
Immunogen Phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr286 found in rat brain CaM Kinase II.
Specificity Specific for the ~50k alpha-CaM Kinase II and the ~60k beta-CaM Kinase II proteins phosphorylated at Thr286. Immunolabeling is blocked by the gamma-phosphatase treatment
Purification Immunogen affinity purified
Plasmids, Primers & others Plasmids, Primers & others CAMK2A products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name CAMK2A (CAMK2A Antibody Abstract)
Background Gene Symbol: CAMK2A
Gene ID 815
UniProt P11275
Pathways WNT Signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction
Application Notes Western Blot 1:1000
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Buffer 10 mM HEPES ( pH 7.5), 0.15M NaCl, 0.1 mg/mL BSA and 50 % Glycerol
Buffer contains: No Preservative
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (pThr286) antibody (ABIN152527) anti-Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (pThr286) antibody
Product cited in: Doran, Ozcan, Cai, Zheng, Fredman, Rymond, Dorweiler, Sluimer, Hsieh, Kuriakose, Tall, Tabas: "CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis." in: The Journal of clinical investigation, Vol. 127, Issue 11, pp. 4075-4089, 2017 (PubMed). Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Gleason, Higashijima, Dallman, Liu, Mandel, Fetcho: "Translocation of CaM kinase II to synaptic sites in vivo." in: Nature neuroscience, Vol. 6, Issue 3, pp. 217-8, 2003 (PubMed).

Meng, Guo, Zhang, Song, Zhang et al.: "Autophosphorylated calcium/calmodulin-dependent protein kinase II alpha (CaMKII alpha) reversibly targets to and phosphorylates N-methyl-D-aspartate receptor subunit 2B (NR2B) in cerebral ischemia ..." in: Brain research, Vol. 967, Issue 1-2, pp. 161-9, 2003 (PubMed).

Hudmon, Schulman: "Neuronal CA2+/calmodulin-dependent protein kinase II: the role of structure and autoregulation in cellular function." in: Annual review of biochemistry, Vol. 71, pp. 473-510, 2002 (PubMed).

Elgersma, Fedorov, Ikonen, Choi, Elgersma, Carvalho, Giese, Silva: "Inhibitory autophosphorylation of CaMKII controls PSD association, plasticity, and learning." in: Neuron, Vol. 36, Issue 3, pp. 493-505, 2002 (PubMed).

Kennedy: "Signal transduction molecules at the glutamatergic postsynaptic membrane." in: Brain research. Brain research reviews, Vol. 26, Issue 2-3, pp. 243-57, 1998 (PubMed).

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