AurB/C antibody (pThr236)

Catalog No. ABIN1531708

Product Details anti-AurB/C Antibody

Target: AurB/C (AURKB/C) (Aurora Kinase B/C (AURKB/C))

Binding Specificity: AA 201-250, pThr236

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AurB/C antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Specificity:

AurB/C (Phospho-Thr236/202) Antibody detects endogenous levels of AurB/C only when phosphorylated at Thr236/202.

PhosphorylationH:T236/202 M:T241/175 R:T239/175

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human AurB/C around the phosphorylation site of Thr236/202.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:10000

Comment:

Unigene-Number: Hs.442658, Hs.98338 (NCBI Gene Symbol: AURKB)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for AurB/C

Target: AurB/C (AURKB/C) (Aurora Kinase B/C (AURKB/C))

Alternative Name: AurB/C (AURKB/C Products)

Background:

Synonyms: AIK2, AIM-1, AIM1, ARK2, AURKB, Aurora- and Ipl1-like midbody-associated protein 1, Aurora-B, Aurora-related kinase 2, Aurora/IPL1-related kinase 2, Serine/threonine protein kinase 12, STK-1, STK12, AIE1, AIE2, AURKC, aurora-C, aurora/Ipl1-related kinase

NCBI Gene Symbol: AURKB

Molecular Weight: 39 kDa

Gene ID: 9212, 6795

OMIM: 604970

UniProt: Q96GD4, Q9UQB9