VAV2 antibody (pTyr142)

Catalog No. ABIN1531758

Product Details anti-VAV2 Antibody

Target: VAV2 (Vav 2 Guanine Nucleotide Exchange Factor (VAV2))

Binding Specificity: AA 108-157, pTyr142

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAV2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Specificity:

VAV2 (Phospho-Tyr142) Antibody detects endogenous levels of VAV2 only when phosphorylated at Tyr142.

PhosphorylationH:Y142 M:Y142

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human VAV2 around the phosphorylation site of Tyr142.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000

Comment:

Unigene-Number: Hs.369921, Hs.689325 (NCBI Gene Symbol: VAV2)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for VAV2

Target: VAV2 (Vav 2 Guanine Nucleotide Exchange Factor (VAV2))

Alternative Name: VAV2 (VAV2 Products)

Synonyms: VAV-2 antibody, 2810040F13Rik antibody, AI847175 antibody, vav guanine nucleotide exchange factor 2 antibody, vav 2 oncogene antibody, VAV2 antibody, Vav2 antibody

Background:

Synonyms: Vav-2 protein, Guanine nucleotide exchange factor VAV2, VAV-2

NCBI Gene Symbol: VAV2

Molecular Weight: 101 kDa

Gene ID: 7410

OMIM: 600428

UniProt: P52735

Pathways: Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway