TCF3 antibody (pThr355)

Catalog No. ABIN1532141

Product Details anti-TCF3 Antibody

Target: TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))

Binding Specificity: AA 321-370, pThr355

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCF3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Specificity:

E2A (Phospho-Thr355) Antibody detects endogenous levels of E2A only when phosphorylated at Thr355.

PhosphorylationH:T355 M:T353 R:T351

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human E2A around the phosphorylation site of Thr355.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.371282 (NCBI Gene Symbol: TCF3)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for TCF3

Target: TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))

Alternative Name: E2A (TCF3 Products)

Synonyms: E2A antibody, E47 antibody, ITF1 antibody, TCF-3 antibody, VDIR antibody, bHLHb21 antibody, tcf3a antibody, zgc:113045 antibody, A1 antibody, AA408400 antibody, ALF2 antibody, AW209082 antibody, E12 antibody, E12/E47 antibody, ME2 antibody, Pan1 antibody, Pan2 antibody, Tcfe2a antibody, bhlhb21 antibody, e2a antibody, itf1 antibody, tcfe2a antibody, vdir antibody, xtcf-3 antibody, xtcf3 antibody, G12 antibody, TCF7L1 antibody, XE3 antibody, transcription factor 3 antibody, transcription factor 3b antibody, transcription factor 3 L homeolog antibody, transcription factor E2a antibody, TCF3 antibody, tcf3b antibody, Tcf3 antibody, tcf3.L antibody, tcfe2a antibody

Background:

Synonyms: E12, Immunoglobulin enhancer binding factor E12/E47, Immunoglobulin transcription factor-1, ITF1, Kappa-E2-binding factor, TCF-3, TCF3, TFE2, transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47), Transcription factor E2-alpha, Tran

NCBI Gene Symbol: TCF3

Molecular Weight: 67 kDa

Gene ID: 6929

OMIM: 147141

UniProt: P15923

Pathways: WNT Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Production of Molecular Mediator of Immune Response