RRN3 antibody (pSer649)

Catalog No. ABIN1532172

Product Details anti-RRN3 Antibody

Target: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Binding Specificity: AA 602-651, pSer649

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRN3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity:

TIF-IA (Phospho-Ser649) Antibody detects endogenous levels of TIF-IA only when phosphorylated at Ser649.

PhosphorylationH:S649

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human TIF-IA around the phosphorylation site of Ser649.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.460078 (NCBI Gene Symbol: RRN3)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for RRN3

Target: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Alternative Name: TIF-IA (RRN3 Products)

Synonyms: RRN3 antibody, DKFZp459B073 antibody, CG16938 antibody, CG3278 antibody, CG5951 antibody, Dmel\\CG3278 antibody, TIF-1A antibody, TIF-IA antibody, Tif-1A antibody, TifIA antibody, dTIF-IA antibody, dyak_GLEANR_13182 antibody, DyakGE12956 antibody, GE12956 antibody, Tif-IA antibody, A-270G1.2 antibody, TIFIA antibody, RGD1305001 antibody, AL023001 antibody, E130302O19Rik antibody, R75565 antibody, Tif1a antibody, RRN3 homolog, RNA polymerase I transcription factor antibody, RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) antibody, CG3278 gene product from transcript CG3278-RA antibody, GE12956 gene product from transcript GE12956-RA antibody, RRN3 homolog, RNA polymerase I transcription factor L homeolog antibody, RRN3 RNA polymerase I transcription factor homolog (yeast) antibody, RRN3 antibody, rrn3 antibody, Tif-IA antibody, Dyak\Tif-IA antibody, rrn3.L antibody, Rrn3 antibody

Background:

Synonyms: RNA polymerase I-specific transcription initiation factor RRN3, RRN3, transcription initiation factor IA

NCBI Gene Symbol: RRN3

Molecular Weight: 74 kDa

Gene ID: 54700

OMIM: 605121

UniProt: Q9NYV6

Pathways: Negative Regulation of intrinsic apoptotic Signaling