P2RX1 antibody (C-Term)

Catalog No. ABIN1537174

Product Details anti-P2RX1 Antibody

Target: P2RX1 (Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1))

Binding Specificity: AA 345-372, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RX1 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This P2RX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-372 amino acids from the C-terminal region of human P2RX1.

Clone: RB36282

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: P2RX1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for P2RX1

Target: P2RX1 (Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1))

Alternative Name: P2RX1 (P2RX1 Products)

Synonyms: p2xr1 antibody, P2X1 antibody, AI323649 antibody, BB122383 antibody, P2x antibody, Pdcd3 antibody, RP-2 antibody, P2XMR antibody, P2X1R antibody, purinergic receptor P2X, ligand-gated ion channel, 1 antibody, purinergic receptor P2X 1 antibody, calcium/calmodulin dependent protein kinase kinase 1 antibody, p2rx1 antibody, P2RX1 antibody, P2rx1 antibody, CAMKK1 antibody

Background: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.

Molecular Weight: 44980

Gene ID: 5023

NCBI Accession: NP_002549

UniProt: P51575

Pathways: Positive Regulation of Endopeptidase Activity