Leupaxin antibody (AA 229-257)

Catalog No. ABIN1538131

Product Details anti-Leupaxin Antibody

Target: Leupaxin (LPXN)

Binding Specificity: AA 229-257

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Leupaxin antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LPXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-257 amino acids from the Central region of human LPXN.

Clone: RB37022

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: LPXN Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for Leupaxin

Target: Leupaxin (LPXN)

Alternative Name: LPXN (LPXN Products)

Synonyms: LDPL antibody, 4933402K05Rik antibody, A530083L21Rik antibody, AV278559 antibody, MGC140379 antibody, leupaxin antibody, hypothetical protein antibody, Leupaxin antibody, LPXN antibody, Lpxn antibody, lpxn antibody, PAAG_03110 antibody, PGTG_11441 antibody

Background: The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molecular Weight: 43332

Gene ID: 9404

NCBI Accession: NP_001137467, NP_004802

UniProt: O60711