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NR3C2 antibody (AA 654-683)

NR3C2 Reactivity: Human WB Host: Rabbit Polyclonal RB36767 unconjugated
Catalog No. ABIN1538559
  • Target See all NR3C2 Antibodies
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    Binding Specificity
    • 16
    • 15
    • 15
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 654-683
    Reactivity
    • 58
    • 45
    • 30
    • 17
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Human
    Host
    • 70
    • 5
    Rabbit
    Clonality
    • 69
    • 6
    Polyclonal
    Conjugate
    • 27
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    This NR3C2 antibody is un-conjugated
    Application
    • 72
    • 39
    • 39
    • 20
    • 14
    • 12
    • 10
    • 9
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    M, Rat, X
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This NR3C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 654-683 amino acids from the Central region of human NR3C2.
    Clone
    RB36767
    Isotype
    Ig Fraction
    Top Product
    Discover our top product NR3C2 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    NR3C2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Expiry Date
    6 months
  • Target
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    Alternative Name
    NR3C2 (NR3C2 Products)
    Synonyms
    mr antibody, si:ch211-189l17.1 antibody, LOC100302443 antibody, NR3C2 antibody, LOC443144 antibody, MLR antibody, MR antibody, MCR antibody, NR3C2VIT antibody, Mlr antibody, mlr antibody, nuclear receptor subfamily 3, group C, member 2 antibody, nuclear receptor subfamily 3 group C member 2 antibody, mineralocorticoid receptor antibody, nuclear receptor subfamily 3 group C member 2 L homeolog antibody, nr3c2 antibody, NR3C2 antibody, LOC443144 antibody, Nr3c2 antibody, nr3c2.L antibody
    Background
    This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.
    Molecular Weight
    107082
    Gene ID
    4306
    NCBI Accession
    NP_000892, NP_001159576
    UniProt
    P08235
    Pathways
    ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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