PPFIA1 antibody (N-Term)

Catalog No. ABIN1539440

Product Details anti-PPFIA1 Antibody

Target: PPFIA1 (Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1))

Binding Specificity: AA 52-80, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPFIA1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PPFIA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-80 amino acids from the N-terminal region of human PPFIA1.

Clone: RB37041

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PPFIA1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for PPFIA1

Target: PPFIA1 (Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1))

Alternative Name: PPFIA1 (PPFIA1 Products)

Synonyms: LIP.1 antibody, LIP1 antibody, LIPRIN antibody, C030014K08Rik antibody, C87158 antibody, PTPRF interacting protein alpha 1 antibody, protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 antibody, PPFIA1 antibody, Ppfia1 antibody

Background: The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Molecular Weight: 135779

Gene ID: 8500

NCBI Accession: NP_003617, NP_803172

UniProt: Q13136