kappa Light Chain antibody

Catalog No. ABIN1539833

Product Details anti-kappa Light Chain Antibody

Target: kappa Light Chain

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This kappa Light Chain antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This Kappa light chain monoclonal antibody is generated from mouse immunized with Kappa light chain recombinant protein.

Clone: HP6053

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:100~1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Kappa light chain Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for kappa Light Chain

Target: kappa Light Chain

Abstract: kappa Light Chain Products

Synonyms: LOC100037688 antibody, B128L antibody, B55L antibody, IgK antibody, TCRAV31S1 antibody, TCRAV40S1 antibody, kappa light chain antibody, immunoglobulin kappa chain variable 8 (V8) antibody, T cell receptor alpha variable 40 antibody, LOC100037688 antibody, Igk-V8 antibody, TRAV40 antibody

Background: Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. There are two types of light chains designated as kappa and lambda (1). Light chain types are based on differences in the amino acid sequence in the constant region of the light chain. If a cell is unsuccessful in rearranging both of its kappa light chain genes, it then attempts to make a lambda light chain. If a cell successfully rearranges a lambda light chain gene, it will be a B cell that makes an immunoglobulin with a lambda light chain (2).

Molecular Weight: 11765

UniProt: P01834