HNMT antibody

Catalog No. ABIN1539866

Product Details anti-HNMT Antibody

Target: HNMT (Histamine N-Methyltransferase (HNMT))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HNMT antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: Purified His-tagged HNMT protein(Fragment) was used to produced this monoclonal antibody.

Clone: 432CT31-4-2

Isotype: IgG1

Application Details

Application Notes: WB: 1:100~1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: HNMT Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for HNMT

Target: HNMT (Histamine N-Methyltransferase (HNMT))

Alternative Name: HNMT (HNMT Products)

Synonyms: HMT antibody, HNMT-S1 antibody, HNMT-S2 antibody, hmt antibody, hnmt antibody, hnmt-s1 antibody, hnmt-s2 antibody, zgc:100917 antibody, HNMT antibody, 1500031F01Rik antibody, AI788969 antibody, HMT A antibody, hnmt-a antibody, hnmt-b antibody, histamine N-methyltransferase antibody, histamine N-methyltransferase S homeolog antibody, histamine N-methyltransferase-like antibody, histamine N-methyltransferase L homeolog antibody, HNMT antibody, hnmt.S antibody, hnmt antibody, Hnmt antibody, LOC100228106 antibody, hnmt.L antibody

Background: In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

Molecular Weight: 33295

Gene ID: 3176

NCBI Accession: NP_001019245, NP_001019246, NP_008826

UniProt: P50135