INA antibody

Catalog No. ABIN1580441

Product Details anti-INA Antibody

Target: INA (Internexin Neuronal Intermediate Filament Protein, alpha (INA))

Reactivity: Mammalian

Host: Mouse

Clonality: Monoclonal

Conjugate: This INA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Purification: conc. tissue culture supernatant

Clone: 1D2

Isotype: IgG1

Application Details

Application Notes: For immunofluorescence try dilutions of 1:500, for immunohistochemistry with ABC or other enzymatic amplification procedures try 1:5,000. For western blots try 1:10,000 dilutions.

Restrictions: For Research Use only

Handling

Format: Liquid

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4°C short term or -20°C long term.

Target Details for INA

Target: INA (Internexin Neuronal Intermediate Filament Protein, alpha (INA))

Abstract: INA Products

Synonyms: NEF5 antibody, NF-66 antibody, TXBP-1 antibody, Inexa antibody, Intlaa antibody, Nf66 antibody, AV028420 antibody, NF66 antibody, ina-A antibody, xefiltin antibody, ina-a antibody, inexa antibody, MGC82496 antibody, INA antibody, si:ch211-67n3.6 antibody, nef5 antibody, xina antibody, nf-66 antibody, txbp-1 antibody, MGC69277 antibody, gefiltin antibody, zgc:110516 antibody, internexin neuronal intermediate filament protein alpha antibody, internexin neuronal intermediate filament protein, alpha antibody, internexin neuronal intermediate filament protein alpha S homeolog antibody, low molecular weight neuronal intermediate filament S homeolog antibody, internexin neuronal intermediate filament protein, alpha a antibody, internexin neuronal intermediate filament protein, alpha b antibody, INA antibody, Ina antibody, ina.S antibody, nif.S antibody, inaa antibody, ina antibody, inab antibody

Background: A-internexin is a Class IV intermediate filament subunit. It is related to but distinct from the better known neurofilament triplet proteins, NF-L, NF-M and NF-H, having similar protein sequence motifs and a similar intron organization. Many classes of mature neurons contain a-internexin in addition to NF-L, NF-M and NF-H, and a-internexin is the major neurofilament protein of developing neurons. In some mature neurons alpha-internexin is the only neurofilament subunit expressed. Antibodies to a-internexin are therefore unique probes to study and classify neuronal types and follow their processes in sections and in tissue culture. In addition the very early developmental expression of a-internexin means its presence is an early and convenient diagnostic feature of neuronal progenitors cells and other cell committed to the neuronal lineage. The use of antibodies to this protein in the study of brain tumors has not been examined to date, but is likely to be of interest. The HGNC name for this protein is INA.