ADAMTS7 antibody (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 7) (N-Term)

Details for Product anti-ADAMTS7 Antibody No. ABIN1583920, Supplier: Log in to see
Antigen
  • ADAM-TS7
  • ADAMTS7B
  • ADAM-TS 7
  • ADAMTS-7
  • COMPase
  • ADAM metallopeptidase with thrombospondin type 1 motif 7
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7
  • ADAM metallopeptidase with thrombospondin type 1 motif, 7
  • ADAMTS7
  • Adamts7
Epitope
N-Term
15
15
5
4
3
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
46
39
39
Host
Rabbit
53
1
Clonality
Polyclonal
Conjugate
This ADAMTS7 antibody is un-conjugated
6
6
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
27
26
15
7
7
5
2
Options
Supplier
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Immunogen KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ADAM-TS7.
Blocking Peptide Blocking peptide for this product available: ABIN1607043
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Purification Antibody was purified by Protein-A affinity chromatography.
Alternative Name ADAM-TS7 (ADAMTS7 Antibody Abstract)
Background

Alternate Names: A disintegrin and metalloproteinase with thrombospondin motifs 7, ADAMTS-7, ADAM-TS 7, ADAM-TS7, COMPase, ADAMTS7

Description: A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS7) is a metalloprotease that degrades COMP. ADAM-TS7 is up-regulated in articular cartilage and synovium from arthritis patients. The spacer domain and the thrombospondin type-1 domain are important for a tight interaction with the extracellular matrix. The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.

UniProt Q9UKP4
Application Notes E: 1:500-1:1,000, WB: 1:100-1:500, IHC: 1:100-1:500
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Each vial contains 0.1 mg IgG in 0.1 mL (1 mg/mL) of PBS pH 7.4, 25 % glycerol, 0.1 mg/mL BSA with 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use Warning: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Handling Advice Minimize freeze-thaw cycles.
Storage -20 °C
Storage Comment Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Expiry Date 12 months
Supplier Images
Immunohistochemistry (IHC) image for anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 7 (ADAMTS7) (N-Term) antibody (ABIN1583920) anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 7 (ADAMTS7) (N-Term) antibody
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