MAPT antibody (Microtubule-Associated Protein tau)

Details for Product anti-MAPT Antibody No. ABIN1585617, Supplier: Log in to see
Antigen
  • DDPAC
  • FTDP-17
  • MAPTL
  • MSTD
  • MTBT1
  • MTBT2
  • PPND
  • TAU
  • AI413597
  • AW045860
  • Mtapt
  • Tau
  • RNPTAU
  • pTau
  • tau
  • xtp
  • MAPT
  • PHF-tau
  • slc6a6
  • taut
  • wu:fc26e12
  • microtubule associated protein tau
  • microtubule-associated protein tau
  • microtubule associated protein tau S homeolog
  • Microtubule-associated protein tau
  • solute carrier family 6 (neurotransmitter transporter), member 6b
  • MAPT
  • Mapt
  • mapt.S
  • LOC5580230
  • CpipJ_CPIJ013260
  • tau
  • slc6a6b
Alternatives
anti-Human MAPT antibody for Western Blotting
Reactivity
Human, Mouse (Murine), Rat (Rattus), Cow (Bovine)
1025
614
595
123
47
43
41
37
25
17
12
9
4
4
4
3
3
3
3
3
2
2
2
1
1
1
1
1
Host
Mouse
928
138
12
7
Clonality (Clone)
Monoclonal ()
Conjugate
This MAPT antibody is un-conjugated
26
11
10
7
6
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
968
336
312
149
96
65
49
31
14
13
12
12
12
9
9
5
4
2
1
Options
Supplier
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Supplier Product No.
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Immunogen Bovine microtubule-associated proteins (MAPs).
Clone TAU-93
Isotype IgG1
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification Antibody was purified by Protein-G affinity chromatography.
Alternative Name Tau (MAPT Antibody Abstract)
Background

Alternate Names: Tau, Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, MAPT, MAPTL, MTBT1

Description: Microtubule-associated protein tau (tau) promotes microtubule assembly and stability, and is involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms play a role in its stabilization. In Alzheimer disease, the neuronal cytoskeleton in the brain is progressively disrupted and replaced by tangles of paired helical filaments (PHF) and straight filaments, mainly composed of hyperphosphorylated forms of tau (PHF-tau or AD P-tau).

UniProt P10636
Pathways MAPK Signaling, Microtubule Dynamics, M Phase, Regulation of Cell Size
Application Notes E: 1:500-1:1,000, WB: 1:100-1:500, IHC: 1:100-1:500
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Each vial contains 0.1 mg IgG1 in 0.1 mL (1 mg/mL) of PBS pH 7.4, 2 % BSA with 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use Warning: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Handling Advice Minimize freeze-thaw cycles.
Storage -20 °C
Storage Comment Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-Microtubule-Associated Protein tau (MAPT) antibody (ABIN1585617) anti-Microtubule-Associated Protein tau (MAPT) antibody
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