EGFL7 antibody
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- Target See all EGFL7 Antibodies
- EGFL7 (EGF-Like-Domain, Multiple 7 (EGFL7))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EGFL7 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)
- Specificity
- Recombinant human EGFL-7 C-Terminus
- Characteristics
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Chromosomal location: 9q34.3
Produced from sera of rabbits immunised with highly pure recombinant human VE-Statin/EGFL-7. - Purification
- Anti-human VE-Statin/EGFL-7 was purified by Protein-A chromatography.
- Isotype
- IgG
- Top Product
- Discover our top product EGFL7 Primary Antibody
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- Application Notes
- Western Blot: use 2-5 µg/mL
- Comment
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Rabbit IG Polyclonal Antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
- Buffer
- PBS
- Handling Advice
- Centrifuge vial prior to opening.
- Storage
- -20 °C
- Storage Comment
- The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.
- Expiry Date
- 6 months
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- Target
- EGFL7 (EGF-Like-Domain, Multiple 7 (EGFL7))
- Alternative Name
- VE-Statin/EGFL-7 (EGFL7 Products)
- Synonyms
- egfl7 antibody, MGC53105 antibody, EGFL7 antibody, zgc:136669 antibody, zgc:152804 antibody, zneu1 antibody, xegfl7 antibody, MGC147423 antibody, VE-statin antibody, Zneu1 antibody, NEU1 antibody, RP11-251M1.2 antibody, VE-STATIN antibody, ZNEU1 antibody, EGF like domain multiple 7 S homeolog antibody, EGF like domain multiple 7 antibody, EGF-like-domain, multiple 7 antibody, EGF-like domain 7 antibody, egfl7.S antibody, EGFL7 antibody, egfl7 antibody, Egfl7 antibody
- Background
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EGFL7 (VE-Statin) is an ∼ 30 kDa secreted protein that contains an Emilin-like (EMI) domain (a multimerization motif), and two epidermal growth factor (EGF) domains, one of which binds calcium. Based on these domains, it has been hypothesized that EGFL7 may self-assemble like extracellular matrix (ECM) proteins and, thus, could incorporate into ECM. EGFL7 has been reported to stimulate cell adhesion as well as motility in a manner similar to ECM proteins. EGFL7 has been shown to be primarily expressed by developing ECs but also by primordial germ cells and some central nervous system neurons. Interestingly, EGFL7 expression markedly decreases in ECs in postnatal life, but can be strongly up-regulated after various tissue injuries that lead to increased angiogenic responses.
Synonyms: EGFL7, NEU1, ZNEU1, VE-STATIN, RP11-251M1.2, NOTCH4-like protein, Vascular endothelial statin - NCBI Accession
- NP_057299, NM_016215
- UniProt
- Q9UHF1
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