ARHGDIB antibody (AA 1-201)

Catalog No. ABIN1678741

Product Details anti-ARHGDIB Antibody

Target: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Binding Specificity: AA 1-201

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGDIB antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MTEKAPEPHV EEDDDDELDS KLNYKPPPQK SLKELQEMDK DDESLIKYKK TLLGDGPVVT DPKAPNVVVT RLTLVCESAP GPITMDLTGD LEALKKETIV LKEGSEYRVK IHFKVNRDIV SGLKYVQHTY RTGVKVDKAT FMVGSYGPRP EEYEFLTPVE EAPKGMLARG TYHNKSFFTD DDKQDHLSWE WNLSIKKEWT E

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human ARHGDIB (NP_001166.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ARHGDIB

Target: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Alternative Name: ARHGDIB (ARHGDIB Products)

Synonyms: ARHGDIB antibody, zgc:65966 antibody, arhgdib antibody, MGC69067 antibody, gdia2 antibody, rhodgi-2 antibody, rhodgi2 antibody, D4 antibody, GDIA2 antibody, GDID4 antibody, LYGDI antibody, Ly-GDI antibody, RAP1GN1 antibody, RhoGDI2 antibody, Gdid4 antibody, Rho GDP dissociation inhibitor (GDI) gamma antibody, Rho GDP dissociation inhibitor (GDI) beta S homeolog antibody, Rho GDP dissociation inhibitor beta antibody, Rho GDP dissociation inhibitor (GDI) beta antibody, Rho, GDP dissociation inhibitor (GDI) beta antibody, arhgdig antibody, arhgdib.S antibody, ARHGDIB antibody, arhgdib antibody, Arhgdib antibody

Background: Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).[supplied by OMIM, Dec 2010],ARHGDIB,D4,GDIA2,GDID4,LYGDI,Ly-GDI,RAP1GN1,RhoGDI2,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,ARHGDIB

Molecular Weight: 22 kDa

Gene ID: 397

UniProt: P52566

Pathways: Caspase Cascade in Apoptosis