ATP6V1B2 antibody (AA 262-511)

Catalog No. ABIN1678792

This Rabbit Polyclonal antibody specifically detects ATP6V1B2 in WB. It exhibits reactivity toward Human.

Quick Overview for ATP6V1B2 antibody (AA 262-511) (ABIN1678792)

Target: ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6V1B2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ATP6V1B2 Antibody

Binding Specificity: AA 262-511

Sequence: NLANDPTIER IITPRLALTT AEFLAYQCEK HVLVILTDMS SYAEALREVS AAREEVPGRR GFPGYMYTDL ATIYERAGRV EGRNGSITQI PILTMPNDDI THPIPDLTGY ITEGQIYVDR QLHNRQIYPP INVLPSLSRL MKSAIGEGMT RKDHADVSNQ LYACYAIGKD VQAMKAVVGE EALTSDDLLY LEFLQKFERN FIAQGPYENR TVFETLDIGW QLLRIFPKEM LKRIPQSTLS EFYPRDSAKH

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 262-511 of human ATP6V1B2 (NP_001684.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATP6V1B2

Target: ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))

Alternative Name: ATP6V1B2

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.,ATP6V1B2,ATP6B1B2,ATP6B2,DOOD,HO57,VATB,VPP3,Vma2,ZLS2,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Neuroscience,ATP6V1B2

Molecular Weight: 56 kDa

Gene ID: 526

UniProt: P21281

Pathways: Transition Metal Ion Homeostasis, Proton Transport