DNAJC2 antibody (AA 1-140)

Catalog No. ABIN1679553

Product Details anti-DNAJC2 Antibody

Target: DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))

Binding Specificity: AA 1-140

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAJC2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MLLLPSAADG RGTAITHALT SASTLCQVEP VGRWFEAFVK RRNRNASASF QELEDKKELS EESEDEELQL EEFPMLKTLD PKDWKNQDHY AVLGLGHVRY KATQRQIKAA HKAMVLKHHP DKRKAAGEPI KEGDNDYFTC

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human DNAJC2 (NP_055192.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DNAJC2

Target: DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))

Alternative Name: DNAJC2 (DNAJC2 Products)

Synonyms: zrf1 antibody, ZRF1 antibody, MPHOSPH11 antibody, MPP11 antibody, ZUO1 antibody, AU020218 antibody, MIDA1 antibody, Zrf1 antibody, Zrf2 antibody, zgc:85671 antibody, DnaJ heat shock protein family (Hsp40) member C2 antibody, DnaJ (Hsp40) homolog, subfamily C, member 2 antibody, dnajc2 antibody, DNAJC2 antibody, Dnajc2 antibody

Background: This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.,DNAJC2,MPHOSPH11,MPP11,ZRF1,ZUO1,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Tumor immunology,Tumor-associated antigens,Signal Transduction,Immunology & Inflammation,DNAJC2

Molecular Weight: 65 kDa/71 kDa

Gene ID: 27000

UniProt: Q99543

Pathways: Chromatin Binding