×
For best experience we recommend to activate Javascript in your browser.
EDNRB antibody (AA 1-100)
EDNRB
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-EDNRB Antibody
(hide)
Target
See all EDNRB Antibodies
EDNRB
(Endothelin Receptor Type B (EDNRB))
Binding Specificity
All epitopes for EDNRB antibodies
AA 1-100
Reactivity
All reactivities for EDNRB antibodies
Human
Host
All hosts for EDNRB antibodies
Rabbit
Clonality
All clonalities for EDNRB antibodies
Polyclonal
Conjugate
All conjugates for EDNRB antibodies
This EDNRB antibody is un-conjugated
Application
All applications for EDNRB antibodies
Western Blotting (WB)
Sequence
MQPPPSLCGR ALVALVLACG LSRIWGEERG FPPDRATPLL QTAEIMTPPT KTLWPKGSNA SLARSLAPAE VPKGDRTAGS PPRTISPPPC QGPIEIKETF
Cross-Reactivity
Human, Mouse
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human EDNRB (NP_001116131.1).
Isotype
IgG
Top Product
Discover our top product EDNRB Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
(hide)
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for EDNRB
(hide)
Target
EDNRB
(Endothelin Receptor Type B (EDNRB))
Alternative Name
EDNRB (EDNRB Products )
Synonyms
ABCDS antibody, ET-B antibody, ET-BR antibody, ETB antibody, ETBR antibody, ETRB antibody, HSCR antibody, HSCR2 antibody, WS4A antibody, Ednra antibody, Etb antibody, ETR-b antibody, ETb antibody, Sox10m1 antibody, EDNRB antibody, abcds antibody, etb antibody, etrb antibody, hscr antibody, hscr2 antibody, endothelin receptor type B antibody, EDNRB antibody, Ednrb antibody, ednrb antibody
Background
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants.,EDNRB,ABCDS,ET-B,ET-BR,ETB,ETB1,ETBR,ETRB,HSCR,HSCR2,WS4A,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),EDNRB
Molecular Weight
48 kDa/49 kDa/59 kDa
Gene ID
1910
UniProt
P24530
Pathways
Cellular Response to Molecule of Bacterial Origin , cAMP Metabolic Process
Recently viewed
(hide)