LONP1 antibody (AA 120-400)

Catalog No. ABIN1680707

Product Details anti-LONP1 Antibody

Target: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Binding Specificity: AA 120-400

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LONP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Sequence: VFPHLPLIAI TRNPVFPRFI KIIEVKNKKL VELLRRKVRL AQPYVGVFLK RDDSNESDVV ESLDEIYHTG TFAQIHEMQD LGDKLRMIVM GHRRVHISRQ LEVEPEEPEA ENKHKPRRKS KRGKKEAEDE LSARHPAELA MEPTPELPAE VLMVEVENVV HEDFQVTEEV KALTAEIVKT IRDIIALNPL YRESVLQMMQ AGQRVVDNPI YLSDMGAALT GAESHELQDV LEETNIPKRL YKALSLLKKE FELSKLQQRL GREVEEKIKQ THRKYLLQEQ L

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-400 of human LONP1 (NP_004784.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LONP1

Target: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Alternative Name: LONP1 (LONP1 Products)

Synonyms: PRSS15 antibody, prss15 antibody, fc64d11 antibody, wu:fc64d11 antibody, LON antibody, LONP antibody, LonHS antibody, PIM1 antibody, hLON antibody, 1200017E13Rik antibody, Prss15 antibody, Lon antibody, lon peptidase 1, mitochondrial antibody, ATP-dependent Lon protease antibody, LONP1 antibody, lonp1 antibody, Lonp1 antibody, PIM1 antibody

Background: This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene.,LONP1,CODASS,LON,LONP,LonHS,PIM1,PRSS15,hLON,Epigenetics & Nuclear Signaling,Cancer,Endocrine & Metabolism,Mitochondrial metabolism,Nucleotide metabolism,LONP1

Molecular Weight: 85 kDa/100 kDa/106 kDa

Gene ID: 9361

UniProt: P36776