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NEDD4 antibody (AA 160-460)
NEDD4
Reactivity: Human
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NEDD4 Antibody
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Target
See all NEDD4 Antibodies
NEDD4
(Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4))
Binding Specificity
All epitopes for NEDD4 antibodies
AA 160-460
Reactivity
All reactivities for NEDD4 antibodies
Human
Host
All hosts for NEDD4 antibodies
Rabbit
Clonality
All clonalities for NEDD4 antibodies
Polyclonal
Conjugate
All conjugates for NEDD4 antibodies
This NEDD4 antibody is un-conjugated
Application
All applications for NEDD4 antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Sequence
GSYSSNGSDF GSCASITSGG SYTNSVISDS SSYTFPPSDD TFLGGNLPSD STSNRSVPNR NTTPCEIFSR STSTDPFVQD DLEHGLEIMK LPVSRNTKIP LKRYSSLVIF PRSPSTTRPT SPTSLCTLLS KGSYQTSHQF IISPSEIAHN EDGTSAKGFL STAVNGLRLS KTICTPGEVR DIRPLHRKGS LQKKIVLSNN TPRQTVCEKS SEGYSCVSVH FTQRKAATLD CETTNGDCKP EMSEIKLNSD SEYIKLMHRT SACLPSSQNV DCQININGEL ERPHSQMNKN HGILRRSISL G
Cross-Reactivity
Human
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 160-460 of human NEDD4 (NP_940682.2).
Isotype
IgG
Top Product
Discover our top product NEDD4 Primary Antibody
Alternatives
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anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4) (AA 801-900) antibody
NEDD4
Reactivity: Human, Rat
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for NEDD4
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Target
NEDD4
(Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4))
Alternative Name
NEDD4 (NEDD4 Products )
Background
This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.,NEDD4,NEDD4-1,RPF1,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Notch Signaling Pathway,Endocrine & Metabolism,Mitochondrial metabolism,Immunology & Inflammation,Neuroscience,NEDD4
Molecular Weight
104 kDa/140 kDa/147 kDa/149 kDa
Gene ID
4734
UniProt
P46934
Pathways
Notch Signaling , Intracellular Steroid Hormone Receptor Signaling Pathway , Skeletal Muscle Fiber Development , Signaling Events mediated by VEGFR1 and VEGFR2
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