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NF-kB p65 antibody (pSer276)

NFkBP65 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1682005
  • Target See all NF-kB p65 (NFkBP65) Antibodies
    NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))
    Binding Specificity
    • 40
    • 31
    • 29
    • 28
    • 28
    • 25
    • 23
    • 23
    • 20
    • 17
    • 16
    • 15
    • 14
    • 11
    • 9
    • 9
    • 8
    • 8
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    pSer276
    Reactivity
    • 531
    • 371
    • 297
    • 41
    • 38
    • 29
    • 24
    • 20
    • 18
    • 15
    • 14
    • 11
    • 5
    • 2
    • 1
    • 1
    Human
    Host
    • 492
    • 43
    • 4
    • 2
    • 1
    Rabbit
    Clonality
    • 458
    • 83
    Polyclonal
    Conjugate
    • 292
    • 30
    • 23
    • 18
    • 17
    • 17
    • 17
    • 17
    • 17
    • 17
    • 14
    • 10
    • 10
    • 10
    • 10
    • 10
    • 9
    • 2
    • 2
    This NF-kB p65 antibody is un-conjugated
    Application
    • 425
    • 203
    • 135
    • 118
    • 110
    • 104
    • 92
    • 78
    • 76
    • 29
    • 25
    • 9
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequence
    RPSDR
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Phosphorylated Antibodies
    Immunogen
    A synthetic phosphorylated peptide around S276 of human RelA (NP_068810.3).
    Isotype
    IgG
    Top Product
    Discover our top product NFkBP65 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IF,1:20 - 1:50
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Dinesh, Rasool et al.: "Berberine inhibits IL-21/IL-21R mediated inflammatory proliferation of fibroblast-like synoviocytes through the attenuation of PI3K/Akt signaling pathway and ameliorates IL-21 mediated ..." in: Cytokine, Vol. 106, pp. 54-66, (2018) (PubMed).

  • Target
    NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))
    Alternative Name
    RELA (NFkBP65 Products)
    Synonyms
    C-Rel antibody, NFKB3 antibody, p65 antibody, NFkB antibody, c-rel antibody, zgc:100833 antibody, Xrel2 antibody, Xrel3 antibody, rel antibody, rel-A antibody, rel2 antibody, rel3 antibody, v-rel antibody, xrel antibody, REL proto-oncogene, NF-kB subunit antibody, RELA proto-oncogene, NF-kB subunit antibody, v-rel reticuloendotheliosis viral oncogene homolog A (avian) antibody, v-rel avian reticuloendotheliosis viral oncogene homolog antibody, v-rel avian reticuloendotheliosis viral oncogene homolog L homeolog antibody, REL antibody, RELA antibody, Rela antibody, Rel antibody, rel antibody, rel.L antibody
    Background
    NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.,NFKB3,p65,NF-kB p65,RELA,CMCU,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,IL-6 Receptor Signaling Pathway,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Cardiovascular,Protein phosphorylation,RELA
    Molecular Weight
    58 kDa/59 kDa/60 kDa
    Gene ID
    5970
    UniProt
    Q04206
    Pathways
    NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades, S100 Proteins
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