PLAA antibody (AA 536-795)

Catalog No. ABIN1682194

Product Details anti-PLAA Antibody

Target: PLAA (Phospholipase A2-Activating Protein (PLAA))

Binding Specificity: AA 536-795

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLAA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PKKEAVTFDQ ANPTQILGKL KELNGTAPEE KKLTEDDLIL LEKILSLICN SSSEKPTVQQ LQILWKAINC PEDIVFPALD ILRLSIKHPS VNENFCNEKE GAQFSSHLIN LLNPKGKPAN QLLALRTFCN CFVGQAGQKL MMSQRESLMS HAIELKSGSN KNIHIALATL ALNYSVCFHK DHNIEGKAQC LSLISTILEV VQDLEATFRL LVALGTLISD DSNAVQLAKS LGVDSQIKKY SSVSEPAKVS ECCRFILNLL

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 536-795 of human PLAA (NP_001026859.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PLAA

Target: PLAA (Phospholipase A2-Activating Protein (PLAA))

Alternative Name: PLAA (PLAA Products)

Synonyms: cb623 antibody, zgc:56568 antibody, zgc:66193 antibody, wu:fc45d08 antibody, wu:fi33e06 antibody, PLAA antibody, doa1 antibody, pla2p antibody, plap antibody, DOA1 antibody, PLA2P antibody, PLAP antibody, 2410007N06 antibody, AI536418 antibody, AU018445 antibody, AW208417 antibody, D4Ertd618e antibody, Ufd3 antibody, Plap antibody, phospholipase A2-activating protein antibody, phospholipase A2 activating protein antibody, phospholipase A2-activating protein L homeolog antibody, phospholipase A2-activating protein S homeolog antibody, phospholipase A2, activating protein antibody, plaa antibody, PLAA antibody, plaa.L antibody, plaa.S antibody, Plaa antibody

Background: Plays a role in protein ubiquitination, sorting and degradation through its association with VCP. Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling (By similarity. May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes. Plays a role in cerebellar Purkinje cell development (By similarity. Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF-alpha- or lipopolysaccharide (LPS-dependent manner, and hence prostaglandin E2 biosynthesis.,PLAA,DOA1,PLA2P,PLAP,NDMSBA,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,PLAA

Molecular Weight: 87 kDa

Gene ID: 9373

UniProt: Q9Y263