7-Sep (AA 307-436) antibody

Catalog No. ABIN1682655

Product Details

Target: 7-Sep

Binding Specificity: AA 307-436

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: NYRSRKLAAV TYNGVDNNKN KGQLTKSPLA QMEEERREHV AKMKKMEMEM EQVFEMKVKE KVQKLKDSEA ELQRRHEQMK KNLEAQHKEL EEKRRQFEDE KANWEAQQRI LEQQNSSRTL EKNKKKGKIF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 307-436 of human Septin 7 (NP_001011553.2).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details

Target: 7-Sep

Background: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.,SEPT7,CDC10,CDC3,NBLA02942,SEPT7A,septin-7,Cell Biology & Developmental Biology,Cell Cycle,Immunology & Inflammation,Cytokines,7-Sep

Molecular Weight: 50 kDa

Gene ID: 989

UniProt: Q16181