SF3A3 antibody (AA 292-501)

Catalog No. ABIN1682671

Product Details anti-SF3A3 Antibody

Target: SF3A3 (Splicing Factor 3a, Subunit 3, 60kDa (SF3A3))

Binding Specificity: AA 292-501

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3A3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: SLESLDTSLF AKNPKSKGTK RDTERNKDIA FLEAQIYEYV EILGEQRHLT HENVQRKQAR TGEEREEEEE EQISESESED EENEIIYNPK NLPLGWDGKP IPYWLYKLHG LNINYNCEIC GNYTYRGPKA FQRHFAEWRH AHGMRCLGIP NTAHFANVTQ IEDAVSLWAK LKLQKASERW QPDTEEEYED SSGNVVNKKT YEDLKRQGLL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 292-501 of human SF3A3 (NP_006793.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SF3A3

Target: SF3A3 (Splicing Factor 3a, Subunit 3, 60kDa (SF3A3))

Alternative Name: SF3A3 (SF3A3 Products)

Synonyms: PRP9 antibody, PRPF9 antibody, SAP61 antibody, SF3a60 antibody, 4930512K19Rik antibody, 60kDa antibody, LRRGT00093 antibody, wu:fi15a06 antibody, wu:fj94f01 antibody, zgc:110227 antibody, splicing factor 3a subunit 3 antibody, splicing factor 3a, subunit 3, 60kDa antibody, splicing factor 3a, subunit 3 antibody, splicing factor 3a subunit 3 S homeolog antibody, SF3A3 antibody, Sf3a3 antibody, sf3a3.S antibody, sf3a3 antibody

Background: This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.,SF3A3,PRP9,PRPF9,SAP61,SF3a60,Epigenetics & Nuclear Signaling,RNA Binding,SF3A3

Molecular Weight: 58 kDa

Gene ID: 10946

UniProt: Q12874

Pathways: Ribonucleoprotein Complex Subunit Organization