TGFBR3 antibody (AA 140-340)

Catalog No. ABIN1683014

Product Details anti-TGFBR3 Antibody

Target: TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))

Binding Specificity: AA 140-340

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGFBR3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ANFSLTAETE ERNFPHGNEH LLNWARKEYG AVTSFTELKI ARNIYIKVGE DQVFPPKCNI GKNFLSLNYL AEYLQPKAAE GCVMSSQPQN EEVHIIELIT PNSNPYSAFQ VDITIDIRPS QEDLEVVKNL ILILKCKKSV NWVIKSFDVK GSLKIIAPNS IGFGKESERS MTMTKSIRDD IPSTQGNLVK WALDNGYSPI T

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 140-340 of human TGFBR3 (NP_003234.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TGFBR3

Target: TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))

Alternative Name: TGFBR3 (TGFBR3 Products)

Synonyms: TGFBR3 antibody, DKFZp469I0915 antibody, BGCAN antibody, betaglycan antibody, 1110036H20Rik antibody, AU015626 antibody, AW215636 antibody, TBRIII antibody, transforming growth factor beta receptor 3 antibody, transforming growth factor, beta receptor III antibody, TGFBR3 antibody, tgfbr3 antibody, Tgfbr3 antibody

Background: This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.,TGFBR3,BGCAN,betaglycan,Signal Transduction,MAPK-P38 Signaling Pathway,Immunology & Inflammation,Cytokines,Cell Intrinsic Innate Immunity Signaling Pathway,Stem Cells,Receptors,TGFBR3

Molecular Weight: 93 kDa

Gene ID: 7049

UniProt: Q03167