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XRCC1 antibody (AA 1-320)
XRCC1
Reactivity: Human
WB, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-XRCC1 Antibody
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Target
See all XRCC1 Antibodies
XRCC1
(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1))
Binding Specificity
All epitopes for XRCC1 antibodies
AA 1-320
Reactivity
All reactivities for XRCC1 antibodies
Human
Host
All hosts for XRCC1 antibodies
Rabbit
Clonality
All clonalities for XRCC1 antibodies
Polyclonal
Conjugate
All conjugates for XRCC1 antibodies
This XRCC1 antibody is un-conjugated
Application
All applications for XRCC1 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Sequence
MPEIRLRHVV SCSSQDSTHC AENLLKADTY RKWRAAKAGE KTISVVLQLE KEEQIHSVDI GNDGSAFVEV LVGSSAGGAG EQDYEVLLVT SSFMSPSESR SGSNPNRVRM FGPDKLVRAA AEKRWDRVKI VCSQPYSKDS PFGLSFVRFH SPPDKDEAEA PSQKVTVTKL GQFRVKEEDE SANSLRPGAL FFSRINKTSP VTASDPAGPS YAAATLQASS AASSASPVSR AIGSTSKPQE SPKGKRKLDL NQEEKKTPSK PPAQLSPSVP KRPKLPAPTR TPATAPVPAR AQGAVTGKPR GEGTEPRRPR AGPEELGKIL
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human XRCC1 (NP_006288.2).
Isotype
IgG
Alternatives
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Application Details
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Application Notes
WB,1:1000 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for XRCC1
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Target
XRCC1
(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1))
Alternative Name
XRCC1 (XRCC1 Products )
Synonyms
xrcc1 antibody, MGC80909 antibody, XRCC1 antibody, rcc antibody, RCC antibody, Xrcc-1 antibody, X-ray repair complementing defective repair in Chinese hamster cells 1 antibody, X-ray repair cross complementing 1 antibody, xrcc1 antibody, XRCC1 antibody, Xrcc1 antibody
Background
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.,XRCC1,RCC,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Endocrine & Metabolism,Nucleotide metabolism,Purine and pyrimidine synthesis,XRCC1
Molecular Weight
69 kDa
Gene ID
7515
UniProt
P18887
Pathways
DNA Damage Repair
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