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GCNT7 antibody (AA 241-430) (Alexa Fluor 350)

GCNT7 Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 350
Catalog No. ABIN1693042
  • Target See all GCNT7 Antibodies
    GCNT7 (Glucosaminyl (N-Acetyl) Transferase Family Member 7 (GCNT7))
    Binding Specificity
    • 14
    • 9
    • 8
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 241-430
    Reactivity
    • 35
    • 4
    • 3
    Human
    Host
    • 35
    Rabbit
    Clonality
    • 35
    Polyclonal
    Conjugate
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GCNT7 antibody is conjugated to Alexa Fluor 350
    Application
    • 35
    • 19
    • 12
    • 12
    • 8
    • 7
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GCNT7
    Isotype
    IgG
    Top Product
    Discover our top product GCNT7 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    GCNT7 (Glucosaminyl (N-Acetyl) Transferase Family Member 7 (GCNT7))
    Alternative Name
    GCNT7 (GCNT7 Products)
    Synonyms
    A330041C17Rik antibody, gnt antibody, C20orf105 antibody, dJ1153D9.2 antibody, gcnt antibody, C17H20orf105 antibody, glucosaminyl (N-acetyl) transferase family member 7 antibody, Gcnt7 antibody, GCNT7 antibody
    Background

    Synonyms: 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase 7, Beta-1, Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7, C20orf105, GCNT, GCNT7, GCNT7_HUMAN, glucosaminyl N-acetyl transferase family member 7.

    Background: Belonging to the glycosyltransferase 14 family, GCNT7, also known as Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7, is a 430 amino acid glycosyltransferase that is localized to the Golgi apparatus. Other members of this family include GCNT1, GCNT2, GCNT3, GCNT4 and GCNT6. GCNT1 has been shown to play an important regulatory role in the biosynthesis of mucin-type O-glycans, which serve as ligands in cell adhesion. Specifically, GCNT1 expression in leukocytes regulates the synthesis of core 2 O-glycans that carry sialyl-Lewis x (sLex) oligosaccharides, which confer high affinity binding to Selectin proteins. Since downregulation of Selectin ligand expression has been shown to inhibit tissue infiltration, glycosyltransferase 14 family members represent potential drug targets for the treatment of inflammatory disorders and other pathologies involving Selectin proteins.

    Gene ID
    140687
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