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G6PC3 antibody (AA 201-300) (Alexa Fluor 350)

G6PC3 Reactivity: Human, Mouse, Rat WB, IF (p) Host: Rabbit Polyclonal Alexa Fluor 350
Catalog No. ABIN1693603
  • Target See all G6PC3 Antibodies
    G6PC3 (Glucose 6-Phosphatase, Catalytic 3 (G6PC3))
    Binding Specificity
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300
    Reactivity
    • 20
    • 18
    • 16
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 20
    Rabbit
    Clonality
    • 20
    Polyclonal
    Conjugate
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This G6PC3 antibody is conjugated to Alexa Fluor 350
    Application
    • 19
    • 12
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Cow,Sheep,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human G6PC3
    Isotype
    IgG
    Top Product
    Discover our top product G6PC3 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    G6PC3 (Glucose 6-Phosphatase, Catalytic 3 (G6PC3))
    Alternative Name
    G6PC3 (G6PC3 Products)
    Synonyms
    SCN4 antibody, UGRP antibody, 0710001K01Rik antibody, AU019276 antibody, AU045429 antibody, AV128920 antibody, AW545836 antibody, glucose-6-phosphatase catalytic subunit 3 antibody, glucose 6 phosphatase, catalytic, 3 antibody, glucose 6 phosphatase catalytic subunit 3 antibody, G6PC3 antibody, G6pc3 antibody
    Background

    Synonyms: G-6-Pase 3, G6Pase 3, G6Pase-beta, Glucose 6 phosphatase, catalytic, 3, Glucose-6-phosphatase 3, Glucose-6-phosphatase beta, SCN4, Ubiquitous glucose-6-phosphatase catalytic subunit-related protein, UGRP,

    Background: Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate (G6P) in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-Alpha, a second form, designated G6Pase-Beta, contributes to blood glucose homeostasis in a wider range of tissues. G6Pase-Beta, also known as SCN4, UGRP or G6PC3 (glucose 6 phosphatase, catalytic, 3), is a 346 amino acid endoplasmic reticulum multi-pass membrane protein that is involved in carbohydrate biosynthesis and the gluconeogenesis pathway. Inhibited by vanadate, G6Pase-Beta hydrolyzes GP6 to glucose in the endoplasmic reticulum. Due to its necessary involvement in normal glucose metabolism, G6Pase-Beta may play an integral role in diabetes and glycogen storage diseases (GSDs).

    Gene ID
    92579
    UniProt
    Q9BUM1
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