C1ORF216 antibody (AA 101-200) (Alexa Fluor 350)

Catalog No. ABIN1693652

Product Details anti-C1ORF216 Antibody (Alexa Fluor 350)

Target: C1ORF216 (Chromosome 1 Open Reading Frame 216 (C1ORF216))

Binding Specificity: AA 101-200

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1ORF216 antibody is conjugated to Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf216

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for C1ORF216

Target: C1ORF216 (Chromosome 1 Open Reading Frame 216 (C1ORF216))

Alternative Name: C1orf216 (C1ORF216 Products)

Synonyms: 7530403E16Rik antibody, AI849033 antibody, RIKEN cDNA 5730409E04Rik gene antibody, chromosome 1 open reading frame 216 antibody, chromosome 1 open reading frame 216 S homeolog antibody, 5730409E04Rik antibody, C1orf216 antibody, c1orf216.S antibody

Background:

Synonyms: 5730409E04Rik, C1orf216, CA216_HUMAN, chromosome 1 open reading frame 216, hypothetical protein LOC127703, UPF0500 protein C1orf216.

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf216 gene product has been provisionally designated C1orf216 pending further characterization.

Gene ID: 127703