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ARID1B antibody (AA 1501-1600) (Alexa Fluor 488)

ARID1B Reactivity: Mouse WB, IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 488
Catalog No. ABIN1695086
  • Target See all ARID1B Antibodies
    ARID1B (AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B))
    Binding Specificity
    • 14
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1501-1600
    Reactivity
    • 32
    • 19
    • 14
    • 3
    • 1
    • 1
    • 1
    Mouse
    Host
    • 44
    • 2
    Rabbit
    Clonality
    • 44
    • 2
    Polyclonal
    Conjugate
    • 19
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARID1B antibody is conjugated to Alexa Fluor 488
    Application
    • 27
    • 12
    • 12
    • 12
    • 10
    • 9
    • 9
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Sheep,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ARID1B
    Isotype
    IgG
    Top Product
    Discover our top product ARID1B Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    ARID1B (AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B))
    Alternative Name
    ARID1B (ARID1B Products)
    Synonyms
    fd07d11 antibody, si:dkey-60a16.3 antibody, wu:fd07d11 antibody, 8030481M12 antibody, 9330189K18Rik antibody, AI836955 antibody, Ardi1b antibody, B230217J03Rik antibody, mKIAA1235 antibody, 6A3-5 antibody, Smcf1 antibody, smcf-1 antibody, BAF250B antibody, BRIGHT antibody, DAN15 antibody, ELD/OSA1 antibody, MRD12 antibody, OSA2 antibody, P250R antibody, AT rich interactive domain 1B (SWI1-like) antibody, AT rich interactive domain 1B (SWI-like) antibody, AT-rich interaction domain 1B antibody, arid1b antibody, Arid1b antibody, ARID1B antibody
    Background

    Synonyms: OSA2, 6A3-5, DAN15, MRD12, P250R, BRIGHT, BAF250B, ELD/OSA1, AT-rich interactive domain-containing protein 1B, ARID domain-containing protein 1B, BRG1-associated factor 250b, BRG1-binding protein hELD/OSA1, Osa homolog 2, hOsa2, ARID1B, KIAA1235

    Background: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Binds DNA non-specifically.

    Gene ID
    57492
    UniProt
    Q8NFD5
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