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GC-Rich Promoter Binding Protein 1 (GPBP1) (AA 11-110) antibody (Alexa Fluor 488)

GPBP1 Reactivity: Mouse WB, IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 488
Catalog No. ABIN1695240
  • Target See all GC-Rich Promoter Binding Protein 1 (GPBP1) Antibodies
    GC-Rich Promoter Binding Protein 1 (GPBP1)
    Binding Specificity
    • 14
    • 3
    • 1
    • 1
    AA 11-110
    Reactivity
    • 18
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 22
    Rabbit
    Clonality
    • 22
    Polyclonal
    Conjugate
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Alexa Fluor 488
    Application
    • 21
    • 12
    • 12
    • 5
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GPBP1/Vasculin
    Isotype
    IgG
    Top Product
    Discover our top product GPBP1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    GC-Rich Promoter Binding Protein 1 (GPBP1)
    Alternative Name
    GPBP1/Vasculin (GPBP1 Products)
    Synonyms
    MGC80437 antibody, Vasculin antibody, DKFZp459A203 antibody, GPBP antibody, SSH6 antibody, VASCULIN antibody, 1700034P14Rik antibody, AU019836 antibody, D230035M11Rik antibody, Gpbp antibody, mGPBP antibody, RGD1305492 antibody, GC-rich promoter binding protein 1 L homeolog antibody, GC-rich promoter binding protein 1 antibody, gpbp1.L antibody, gpbp1 antibody, GPBP1 antibody, Gpbp1 antibody
    Background

    Synonyms: DKFZp761C169, GC rich promoter binding protein 1, GC-rich promoter-binding protein 1, GPBP, Gpbp1, GPBP1_HUMAN, MGC126339, SSH6, Vascular wall linked, Vascular wall-linked protein, Vasculin.

    Background: Vascular wall-linked protein, or Vasculin, is primarily expressed in the arterial wall and in plasma. It is also differentially expressed in human atherogenesis. Alternative splicing of exon 3 of the Vasculin gene produces three variants. Vasculin binds to and activates the minimal self-sufficient promoter element (MSPE) of the mouse Ada gene promoter and binds to and partially suppresses the GC-rich promoter of the nonhomologous human TOP2A gene promoter. It acts as a nuclear factor that can form complexes with TATA-binding proteins, transcription factors TFIIB and TFIIF, RNA polymerase II and p300. The regulated expression of Vasculin in plaques suggests that it may be involved in atherogenesis, and its presence in plasma may implicate Vasculin as a marker for atherosclerosis.

    Gene ID
    65056
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