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GCHFR antibody (AA 21-60) (Alexa Fluor 555)

GCHFR Reactivity: Rat IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 555
Catalog No. ABIN1697188
  • Target See all GCHFR Antibodies
    GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))
    Binding Specificity
    • 14
    • 14
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    AA 21-60
    Reactivity
    • 41
    • 20
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    Rat
    Host
    • 50
    • 5
    Rabbit
    Clonality
    • 50
    • 5
    Polyclonal
    Conjugate
    • 21
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GCHFR antibody is conjugated to Alexa Fluor 555
    Application
    • 25
    • 22
    • 12
    • 12
    • 10
    • 4
    • 3
    • 3
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse,Cow,Pig,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GCHFR
    Isotype
    IgG
    Top Product
    Discover our top product GCHFR Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))
    Alternative Name
    GCHFR (GCHFR Products)
    Synonyms
    GFRP antibody, HsT16933 antibody, P35 antibody, 2010323F13Rik antibody, GTP cyclohydrolase I feedback regulator antibody, GCHFR antibody, Gchfr antibody
    Background

    Synonyms: GCHFR, GFRP, GFRP_HUMAN, GTP cyclohydrolase 1 feedback regulatory protein, GTP cyclohydrolase I feedback regulator, GTP cyclohydrolase I feedback regulatory protein, HsT16933, MGC138467, MGC138469, p35.

    Background: GTP cyclohydrolase I feedback regulatory protein (GFRP) is encoded by the gene GCHFR. GFRP mediates feedback inhibition of GTP cyclohydrolase I activity by tetrahydrobiopterin. GFRP also acts as a mediator for the stimulatory effect of phenylalanine on enzyme activity. L-phenylalanine reverses this inhibition. The molecular weight of GFRP is approximately 9.5 kDa although cross-linking experiments have shown that GFRP is usually found as a homodimer or as a pentamer. 15q15.

    Gene ID
    2644
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