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GNPTAB antibody (AA 1-100) (Alexa Fluor 647)

GNPTAB Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 647
Catalog No. ABIN1699638
  • Target See all GNPTAB Antibodies
    GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))
    Binding Specificity
    • 15
    • 14
    • 1
    • 1
    • 1
    AA 1-100
    Reactivity
    • 32
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 32
    Rabbit
    Clonality
    • 32
    Polyclonal
    Conjugate
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This GNPTAB antibody is conjugated to Alexa Fluor 647
    Application
    • 25
    • 25
    • 18
    • 6
    • 6
    • 6
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human N-acetylglucosamine-1-phosphotransferase subunit alpha
    Isotype
    IgG
    Top Product
    Discover our top product GNPTAB Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))
    Alternative Name
    GNPTAB (GNPTAB Products)
    Synonyms
    si:ch211-234f20.3 antibody, wu:fd55d09 antibody, zgc:122985 antibody, zgc:158502 antibody, GNPTA antibody, ICD antibody, EG432486 antibody, mKIAA1208 antibody, RGD1564821 antibody, N-acetylglucosamine-1-phosphate transferase alpha and beta subunits antibody, N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits antibody, N-acetylglucosamine-1-phosphotransferase subunits alpha/beta antibody, GNPTAB antibody, gnptab antibody, LOC100175423 antibody, Gnptab antibody
    Background

    Synonyms: N-acetylglucosamine-1-phosphotransferase subunit alpha, EC=2.7.8.17, GlcNAc-1-phosphotransferase subunits alpha/beta, GNPTA, GNPTA_HUMAN, Gnptab, KIAA1208, Stealth protein GNPTAB, UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta.

    Background: This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.[provided by RefSeq, May 2010].

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