ENOSF1 antibody (AA 351-443) (Biotin)

Catalog No. ABIN1700139

Product Details anti-ENOSF1 Antibody (Biotin)

Target: ENOSF1 (Enolase Superfamily Member 1 (ENOSF1))

Binding Specificity: AA 351-443

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENOSF1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Dog,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ENOSF1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ENOSF1

Target: ENOSF1 (Enolase Superfamily Member 1 (ENOSF1))

Alternative Name: ENOSF1 (ENOSF1 Products)

Synonyms: HSRTSBETA antibody, RTS antibody, TYMSAS antibody, enolase superfamily member 1 antibody, enolase superfamily member 1 S homeolog antibody, ENOSF1 antibody, enosf1.S antibody

Background:

Synonyms: Enolase superfamily member 1, ENOSF 1, HSRTSBETA, RTS alpha, RTS, RTS beta, RTS beta protein, TYMSAS,

Background: The rTS gene codes for a naturally occurring antisense RNA to thymidylate synthase (TS) mRNA and two proteins (rTSalpha and rTSbeta (also known as ENOSF1)). The role of the major protein product of rTS, ENOSF1 has been linked to alterations in TS protein expression, but the precise function of ENOSF1 is unknown. Expression of rTS is associated with growth arrest in cell culture, but its overexpression has been noted in cells resistant to anticancer drugs such as 5-fluorouracil and methotrexate. Studies have shown that increased expression of ENOSF1 is associated with the decrease in TS protein expression due to production of novel, diffusible signal molecules.