ZFAND5 antibody (AA 121-213) (Biotin)

Catalog No. ABIN1700823

Product Details anti-ZFAND5 Antibody (Biotin)

Target: ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))

Binding Specificity: AA 121-213

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFAND5 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZFAND5

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ZFAND5

Target: ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))

Alternative Name: ZFAND5 (ZFAND5 Products)

Synonyms: 2310057A04Rik antibody, 5830475F03Rik antibody, AA415485 antibody, Za20d2 antibody, Zfp216 antibody, ZA20D2 antibody, ZFAND5A antibody, ZNF216 antibody, wu:fi29f06 antibody, za20d2l antibody, zgc:56057 antibody, za20d2 antibody, zfand5 antibody, zfand5-a antibody, zfand5-b antibody, zfand5a antibody, znf216 antibody, id:ibd2892 antibody, wu:fb16d02 antibody, wu:fc67h07 antibody, zgc:73363 antibody, zinc finger, AN1-type domain 5 antibody, zinc finger AN1-type containing 5 antibody, zinc finger, AN1-type domain 5b antibody, zinc finger AN1-type containing 5 L homeolog antibody, zinc finger, AN1-type domain 5a antibody, Zfand5 antibody, ZFAND5 antibody, zfand5b antibody, zfand5.L antibody, zfand5a antibody

Background:

Synonyms: ZA20D2, ZNF216, ZFAND5A, AN1-type zinc finger protein 5, Zinc finger A20 domain-containing protein 2, Zinc finger protein 216, ZFAND5

Background: Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.

Gene ID: 7763

UniProt: O76080

Pathways: Platelet-derived growth Factor Receptor Signaling