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EYA3 antibody (AA 371-470) (Biotin)

EYA3 Reactivity: Human WB, ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1701246
  • Target See all EYA3 Antibodies
    EYA3 (Eyes Absent Homolog 3 (EYA3))
    Binding Specificity
    • 14
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 371-470
    Reactivity
    • 31
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    Human
    Host
    • 31
    Rabbit
    Clonality
    • 31
    Polyclonal
    Conjugate
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EYA3 antibody is conjugated to Biotin
    Application
    • 28
    • 13
    • 13
    • 10
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human EYA3
    Isotype
    IgG
    Top Product
    Discover our top product EYA3 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    EYA3 (Eyes Absent Homolog 3 (EYA3))
    Alternative Name
    EYA3 (EYA3 Products)
    Synonyms
    zgc:152966 antibody, si:ch211-195b13.2 antibody, Xeya3 antibody, MGC85199 antibody, EYA3 antibody, AI844637 antibody, EYA transcriptional coactivator and phosphatase 3 antibody, EYA transcriptional coactivator and phosphatase 3 L homeolog antibody, eya3 antibody, eya3.L antibody, EYA3 antibody, Eya3 antibody
    Background

    Synonyms: AI844637, DKFZp686C132, EYA3, EYA3_HUMAN, Eyes absent 3, Eyes absent 3 homolog Drosophila, Eyes absent homolog 3, OTTMUSP00000010370, RP11-460I13.4, RP23-442A20.1.

    Background: EYA3 is a 573 amino acid protein that localizes to both the nucleus and the cytoplasm and is one of several mammalian homologs of the Drosophila Eya (eyes absent) protein. Existing as two alternatively spliced isoforms, EYA3 possesses magnesium-catalyzed phosphatase activity and is thought to play a role in transcriptional regulation during organogenesis. Specifically, EYA3 interacts with proteins such as Six1 and, via this interaction, functions to activate the expression of genes that are involved in cellular proliferation and organ development. Upon DNA damage, EYA3 may be phosphorylated by ATM or ATR. The gene encoding EYA3 maps to chromosome 1, which spans about 260 million base pairs and comprises nearly 8 % of the human genome.

    Gene ID
    2140
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
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