FOXI1 antibody (AA 101-200) (Cy5)

Catalog No. ABIN1704287

Product Details anti-FOXI1 Antibody (Cy5)

Target: FOXI1 (Forkhead Box I1 (FOXI1))

Binding Specificity: AA 101-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXI1 antibody is conjugated to Cy5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FOXI1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FOXI1

Target: FOXI1 (Forkhead Box I1 (FOXI1))

Alternative Name: FOXI1 (FOXI1 Products)

Synonyms: FKH10 antibody, FKHL10 antibody, FREAC-6 antibody, FREAC6 antibody, HFH-3 antibody, HFH3 antibody, 5830401E05Rik antibody, Fkh10 antibody, Hfh3 antibody, cb724 antibody, foo antibody, Xfoxi1a antibody, ema antibody, foxi1a antibody, foxi1e antibody, xema antibody, xfoxi1 antibody, FoxI1e antibody, Xema antibody, fkhl10 antibody, freac6 antibody, hfh3 antibody, FOXI1 antibody, forkhead box I1 antibody, forkhead box i1 antibody, forkhead box I1 L homeolog antibody, forkhead box protein I1 antibody, FOXI1 antibody, Foxi1 antibody, foxi1 antibody, foxi1.L antibody, CC1G_14832 antibody

Background:

Synonyms: FKH10, FKHL10, Forkhead Drosophila like 10, Forkhead box I1, Forkhead box protein I1, Forkhead like 10, Forkhead related activator 6, Forkhead related transcription factor 6, Forkhead-related protein FKHL10, FREAC 6, FREAC6, Hepatocyte nuclear factor 3 forkhead homolog 3, HFH 3, HFH3, HNF 3/fork head homolog 3, HNF-3 fork-head homolog 3, Human HNF-3 fork-head homolog-3 HFH-3 mRNA complete cds, MGC34197, FOXI1_HUMAN.

Background: FOXI1 is a member of the FOX family of transcription factors. The FOX family is a large group of proteins (consisting of at least 43 members) that share a common DNA binding domain termed winged-helix or forkhead domain. FOX transcription factors play important roles in development, differentiation, aging and hormone responsiveness. Localizing to the nucleus, FOXI1 functions as a transcription factor. Mice with mutated forms of FOXI1 show defects in ear development, implying that FOXI1 plays a significant role in the developmental pathway of ears and, in particular, the cochlea and vestibulum. FOXI1 is an upstream transcription regulator of Pendrin (a protein associated with deafness), suggesting a role for FOXI1 in the pathogenesis of Pendred syndrome (PS), a condition of nonsyndromic hearing loss and enlarged vestibular aqueduct (EVA).

Gene ID: 2299