LRRC23 antibody (AA 251-343) (Cy5)

Catalog No. ABIN1704590

Product Details anti-LRRC23 Antibody (Cy5)

Target: LRRC23 (Leucine Rich Repeat Containing 23 (LRRC23))

Binding Specificity: AA 251-343

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC23 antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LRRC23

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LRRC23

Target: LRRC23 (Leucine Rich Repeat Containing 23 (LRRC23))

Alternative Name: LRRC23 (LRRC23 Products)

Synonyms: LRPB7 antibody, 4921537K05Rik antibody, B7 antibody, Lrpb7 antibody, leucine rich repeat containing 23 antibody, LRRC23 antibody, Lrrc23 antibody

Background:

Synonyms: Leucine rich protein B7, Leucine rich repeat containing 23, Leucine rich repeat containing protein 23, Lrpb7, LRC23_HUMAN.

Background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å,/ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. LRRC23 (leucine-rich repeat-containing protein 23), also known as leucine-rich protein B7, is a 343 amino acid protein that contains eight LRR (leucine-rich) repeasts and one LRRCT domain. LRRC23 exists as two alternatively spliced isoforms and is encoded by a gene mapping to chromosome 12.

Gene ID: 10233