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DAZ4 antibody (AA 51-150) (Cy5)

DAZ4 Reactivity: Mouse WB, IF (cc), IF (p) Host: Rabbit Polyclonal Cy5
Catalog No. ABIN1705117
  • Target See all DAZ4 Antibodies
    DAZ4 (Deleted In Azoospermia 4 (DAZ4))
    Binding Specificity
    • 14
    • 7
    • 7
    • 6
    • 6
    • 3
    • 1
    • 1
    AA 51-150
    Reactivity
    • 29
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Mouse
    Host
    • 42
    • 1
    Rabbit
    Clonality
    • 43
    Polyclonal
    Conjugate
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This DAZ4 antibody is conjugated to Cy5
    Application
    • 35
    • 18
    • 16
    • 12
    • 12
    • 7
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human DAZ4
    Isotype
    IgG
    Top Product
    Discover our top product DAZ4 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    DAZ4 (Deleted In Azoospermia 4 (DAZ4))
    Alternative Name
    DAZ4 (DAZ4 Products)
    Synonyms
    pDP1680 antibody, pDP1681 antibody, DAZ4 antibody, deleted in azoospermia 4 antibody, DAZ4 antibody
    Background

    Synonyms: DAZ4, Deleted in azoospermia 4, Deleted in azoospermia protein 4.

    Background: Spermatogenesis is the process by which male spermatogonia develop into mature spermatozoa. DAZ (deleted in azoospermia) are RNA-binding proteins that play an essential role in spermatogenesis. DAZ proteins influence the first stages of spermatogenesis and the maintenance of germ cell populations. DAZ proteins (DAZ1, DAZ2, DAZ3, DAZ4 and DAZ5) are encoded by separate genes on chromosome Y, each of which contain an AZFc domain in their coding region. DAZ proteins localize to the nucleus of spermatogonia, but relocate to the cytoplasm during meiosis. DAZ proteins contain an RRM (RNA recognition motif) domain that may regulate mRNA translation by binding to the 3?UTR. Deletions in the genes encoding DAZ proteins may cause azoospermia or oligospermia which can lead to male infertility. DAZ4 (deleted in azoospermia 4), also known as pDP1680 or pDP1681, is a 579 amino acid testis specific protein that contains nine DAZ-like domains and two RNA recognition motifs (RRM). DAZ4 exists as two alternatively spliced isoforms.

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