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GRB14 antibody (AA 221-320) (Cy7)

GRB14 Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal Cy7
Catalog No. ABIN1707723
  • Target See all GRB14 Antibodies
    GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))
    Binding Specificity
    • 14
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 221-320
    Reactivity
    • 30
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 30
    Rabbit
    Clonality
    • 30
    Polyclonal
    Conjugate
    • 13
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRB14 antibody is conjugated to Cy7
    Application
    • 12
    • 12
    • 12
    • 11
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Specificity
    This antibody may also detect the similar protein GRB10 due to an 83 % sequence similarity in the immunogen sequence.
    Cross-Reactivity
    Human
    Predicted Reactivity
    Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GRB 14
    Isotype
    IgG
    Top Product
    Discover our top product GRB14 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))
    Alternative Name
    GRB 14 (GRB14 Products)
    Synonyms
    GRB14 antibody, AI505286 antibody, growth factor receptor bound protein 14 antibody, GRB14 antibody, grb14 antibody, Grb14 antibody
    Background

    Synonyms: Growth factor receptor-bound protein 14, GRB14 adapter protein, GRB14

    Background: Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.

    Gene ID
    2888
    UniProt
    Q14449
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