GPR58 antibody (AA 61-160)

Catalog No. ABIN1713522

Product Details anti-GPR58 Antibody

Target: GPR58 (TAAR2) (Trace Amine Associated Receptor 2 (TAAR2))

Binding Specificity: AA 61-160

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR58 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPR58

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GPR58

Target: GPR58 (TAAR2) (Trace Amine Associated Receptor 2 (TAAR2))

Alternative Name: GPR58 (TAAR2 Products)

Synonyms: GPR58 antibody, Gm224 antibody, Gm225 antibody, Gpr58 antibody, Tarr2 antibody, trace amine associated receptor 2 (gene/pseudogene) antibody, trace amine-associated receptor 2 antibody, trace amine associated receptor 2 antibody, TAAR2 antibody, Taar2 antibody

Background:

Synonyms: G protein coupled receptor 58, phBL5, GPCR 58, GPR 58, TAAR2, Trace amine associated receptor 2.

Background: Trace amines are endogenous molecules structurally related to classical biogenic amines that are linked to psychiatric conditions. A family of G-protein coupled receptors referred to as trace-amine-associated receptors (TAAR) are activated by trace amines and are present in very low levels in mammalian tissue. TAAR?s contain several structural features that are similar to the rhodopsin beta-adrenergic receptor superfamily, including the positions of the seven transmembrane regions that provide common ligand-binding pockets as well as the short N- and C-terminal domains. TAAR proteins are potential targets for drugs of abuse, such as amphetamine and MDMA, as well as neuropsychiatric disorders including schizophrenia, depression, and attention deficit disorder. TAAR-1 is a 340 amino acid protein that increases intracellular cAMP accumulation in response to beta-phenylethylamine and tyramine. TAAR-1 is associated with the detection of social cues, illustrating its significance as a therapeutic target.

Gene ID: 9287