TIFA antibody (AA 51-150)

Catalog No. ABIN1713580

Product Details anti-TIFA Antibody

Target: TIFA (TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA))

Binding Specificity: AA 51-150

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIFA antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TIFA

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TIFA

Target: TIFA (TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA))

Alternative Name: TIFA (TIFA Products)

Synonyms: TIFA antibody, xtifa antibody, T2BP antibody, T6BP antibody, TIFAA antibody, T2bp antibody, Ab2-389 antibody, TRAF interacting protein with forkhead associated domain antibody, TRAF-interacting protein with forkhead-associated domain antibody, TRAF-interacting protein with forkhead-associated domain S homeolog antibody, TIFA antibody, tifa antibody, Tifa antibody, tifa.S antibody

Background:

Synonyms: Putative MAPK activating protein PM14, Putative MAPK-activating protein PM14, Putative NF kappa B activating protein 20, Putative NF-kappa-B-activating protein 20, T2BP, TA, TA_HUMAN, TRAF interacting protein with FHA domain containing protein A, TRAF-interacting protein with FHA domain-containing protein A, TRAF2 binding protein, TRAF2-binding protein.

Background: Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.