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GABPA antibody (AA 51-150)

GABPA Reactivity: Human, Rat WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1714176
  • Target See all GABPA Antibodies
    GABPA (GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA))
    Binding Specificity
    • 14
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reactivity
    • 56
    • 22
    • 10
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 47
    • 9
    Rabbit
    Clonality
    • 48
    • 8
    Polyclonal
    Conjugate
    • 29
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GABPA antibody is un-conjugated
    Application
    • 51
    • 26
    • 12
    • 12
    • 12
    • 11
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human, Rat
    Predicted Reactivity
    Mouse,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GABPA/NRF2A
    Isotype
    IgG
    Top Product
    Discover our top product GABPA Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Chang, Wu, Xu, Liao, Wu, Cheng: "Scopoletin Protects against Methylglyoxal-Induced Hyperglycemia and Insulin Resistance Mediated by Suppression of Advanced Glycation Endproducts (AGEs) Generation and Anti-Glycation." in: Molecules (Basel, Switzerland), Vol. 20, Issue 2, pp. 2786-801, (2015) (PubMed).

  • Target
    GABPA (GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA))
    Alternative Name
    GABPA/NRF2A (GABPA Products)
    Synonyms
    gabpa-A antibody, XrpFI antibody, X-alpha1 antibody, GABPA antibody, nft2 antibody, nrf2 antibody, nrf2a antibody, e4tf1a antibody, e4tf1-60 antibody, Nrf-2alpha antibody, Nrf2a antibody, E4TF1-60 antibody, E4TF1A antibody, NFT2 antibody, NRF2 antibody, NRF2A antibody, RCH04A07 antibody, GABPalpha antibody, e4tf antibody, wu:fc12d11 antibody, GA binding protein transcription factor alpha subunit S homeolog antibody, GA binding protein transcription factor alpha subunit antibody, GA binding protein transcription factor, alpha subunit antibody, GA binding protein transcription factor alpha subunit L homeolog antibody, GA repeat binding protein, alpha antibody, gabpa.S antibody, GABPA antibody, gabpa antibody, Gabpa antibody, gabpa.L antibody
    Background

    Synonyms: E4TF 1A, E4TF1 60, E4TF1A, GA binding protein alpha chain, GA binding protein transcription factor alpha subunit 60 kDa, GA binding protein transcription factor alpha subunit, GA-binding protein alpha chain, GABP A, GABP alpha subunit, GABP alpha subunit, GABP subunit alpha, Gabpa, GABPA_HUMAN, Human nuclear respiratory factor 2 subunit alpha, NFT 2, NFT2, NRF 2, NRF 2A, NRF2, NRF2A, Nuclear respiratory factor 2 alpha subunit, Nuclear respiratory factor 2 subunit alpha, Nuclear respiratory factor 2 subunit alpha, RCH04A07, Transcription factor E4TF1 60, Transcription factor E4TF1 60, Transcription factor E4TF1-60.

    Background: The transcription factor GA-binding protein (GABP) is composed of two subunits, the Ets-related GABP-alpha and a GABP-alpha-associated subunit, GABP beta. GABP alpha binds to a specific DNA sequence and GABP beta exists as b1 and b2 splice variants that differ in their C-termini. In primary neuronal cultures, GABP beta is expressed in both the cytoplasm and the nucleus, whereas GABP alpha is expressed mainly in the nucleus. GABP is constitutively expressed as either a GABP alpha beta heterodimer or a GABP alpha b heterotetramer, both of which can modify GABP-dependent transcription in vitro and in vivo. The GABP alpha beta tetrameric complex performs many different functions, such as stimulating transcription of the adenovirus E4 gene, differentially activating BRCA1 expression in human breast cell lines, potentiating Tat-mediated activation of long terminal repeat promoter transcription and viral replication in certain cell types, acting as a coordinator of mitochrondrial and nuclear transcription for cytochrome oxidase in neurons and assisting in the regulation of rpL32 gene transcription.

    Gene ID
    2551
    Pathways
    Myometrial Relaxation and Contraction
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