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EXTL3 antibody (AA 351-450)

EXTL3 Reactivity: Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1714441
  • Target See all EXTL3 Antibodies
    EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))
    Binding Specificity
    • 14
    • 14
    • 7
    • 5
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 351-450
    Reactivity
    • 45
    • 15
    • 10
    • 1
    Rat
    Host
    • 59
    Rabbit
    Clonality
    • 58
    Polyclonal
    Conjugate
    • 18
    • 6
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This EXTL3 antibody is un-conjugated
    Application
    • 48
    • 30
    • 27
    • 12
    • 12
    • 10
    • 8
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse,Dog,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human EXTL3
    Isotype
    IgG
    Top Product
    Discover our top product EXTL3 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))
    Alternative Name
    EXTL3 (EXTL3 Products)
    Synonyms
    BcDNA:LD21192 antibody, Botv antibody, CG15110 antibody, DEXT3 antibody, DEXTL3 antibody, Dextl3 antibody, Dmel\\CG15110 antibody, Extl3 antibody, 2900009G18Rik antibody, AU040105 antibody, Ext1l antibody, mKIAA0519 antibody, BOTV antibody, EXTL1L antibody, EXTR1 antibody, REGR antibody, RPR antibody, Regr antibody, brother of tout-velu antibody, exostoses (multiple)-like 3 antibody, exostosin like glycosyltransferase 3 antibody, exostosin-like glycosyltransferase 3 antibody, botv antibody, Extl3 antibody, EXTL3 antibody
    Background

    Synonyms: botv, DKFZp686C2342, Exostoses multiple-like 3, Exostoses-like 3, Exostosin-like 3, EXT-related protein 1, EXTL1L, EXTL3, EXTL3_HUMAN, EXTR1, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferas, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Hereditary multiple exostoses gene isolog, KIAA0519, Multiple exostosis-like protein 3, Putative tumor suppressor protein EXTL3, REG, Reg receptor, REGR, RPR.

    Background: EXTL3 is a member of the EXT (hereditary multiple exostosin) gene family of tumor suppressors encoding glycosyltransferases involved in heparan sulfate (HS) biosynthesis. Within this family, the C-terminus is conserved between all members from C. elegans to vertebrates. EXTL3 is a ubiquitously expressed, developmentally regulated, single-pass type II membrane protein that localizes to the endoplasmic reticulum membrane. EXTL3 adds N-acetylglucosamine (GlcNAc) to the polysaccharide-protein linkage region and to the growing HS chain suggesting that it plays a role in both the initiation and elongation of HS chains. In addition, EXTL3 may act as a Reg receptor, binding Reg via its N-terminus.

    Gene ID
    2137
    Pathways
    Glycosaminoglycan Metabolic Process, ER-Nucleus Signaling
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